2026-05-11T22:02:10Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/93362024-07-03T00:05:19Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594
Solas Luera, Marta
542
600
0000-0002-0052-7270
Renedo Peña, Lorena
577faa28-7419-49ac-9b78-2a6cb4c9c7ca
600
Suárez Pantiga, Samuel
544
600
0000-0002-4249-7807
Sanz Díez, Roberto
531
600
0000-0003-2830-0892
2024-07-02T07:48:26Z
2024-07-02T07:48:26Z
2023-05-24
1615-4150
http://hdl.handle.net/10259/9336
10.1002/adsc.202300300
1615-4169
A gold-catalyzed cascade double cyclization reaction has been designed to synthesize heterobiaryl compounds such as furanyl and pyrrolyl 2H-chromenes from bis(alkynyl)-1,2-diols and 1,2-amino alcohols. The starting materials are readily available from biomass platform molecules such as α-hydroxy acids and α-amino acids. The process involves an initial heterocyclodehydration step enabling the formation of the furan or pyrrole ring, followed by an alkyne hydroarylation to form the chromene core.
We gratefully acknowledge Ministerio de Ciencia e Innovación MCIN/AEI/10.13039/501100011033 (PID2020–115789GB-C21), and Junta de Castilla y León and FEDER (BU049P20) for financial support. M.S. and L.R. thank Junta de Castilla y León (Consejería de Educación) and Fondo Social Europeo for predoctoral contracts. S.S.-P. thanks a Ramón y Cajal (RYC2021-031533-I) contract funded by MCIN/AEI/10.13039/501100011033 and European Union “NextGenerationEU”/PRTR.
application/pdf
eng
Wiley
Advanced Synthesis & Catalysis. 2023, V. 365, n. 12, p. 2049-2056
https://doi.org/10.1002/adsc.202300300
Atribución-NoComercial 4.0 Internacional
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
Annulation
Chromenes
Furans
Gold
Hydroarylation
Pyrroles
Química orgánica
Chemistry, Organic
Synthesis of 4‐Furan‐ and 4‐Pyrrol‐3‐yl‐2H‐chromenes from Naturally‐occurring Compounds by Gold(I)‐Catalyed Domino Reactions
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Advanced Synthesis & Catalysis
365
12
2049
2056
THUMBNAIL
Solas-asc_2023.pdf.jpg
Solas-asc_2023.pdf.jpg
IM Thumbnail
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5005
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LICENSE
license.txt
license.txt
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https://riubu.ubu.es/bitstream/10259/9336/3/license.txt
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CC-LICENSE
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ORIGINAL
Solas-asc_2023.pdf
Solas-asc_2023.pdf
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https://riubu.ubu.es/bitstream/10259/9336/1/Solas-asc_2023.pdf
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10259/9336
oai:riubu.ubu.es:10259/9336
2024-07-03 02:05:19.345
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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