RT info:eu-repo/semantics/bachelorThesis T1 Recuperación de polifenoles presentes en salvado de trigo y piel de cebolla mediante un proceso combinado de extracción asistida por ultrasonidos y nanofiltración A1 Díez Carretero, Paula A2 Universidad de Burgos. Departamento de Biotecnología y Ciencia de los Alimentos K1 Wheat bran K1 Onion skin waste K1 Polyohenols K1 Ultrasound-assisted extraction K1 Nanofiltration K1 Antioxidant activity K1 Flavonoids K1 Ferulic acid K1 Quercetin K1 Ingeniería Química K1 Chemical engineering K1 Alimentos K1 Food AB Wheat bran and onion skin waste are agri-food by-products generated in large quantitiesannually. Their valorization represents an important opportunity, linked to sustainability, forobtaining bioactive compounds with beneficial properties. These by-products are notable fortheir high content of bioactive compounds, specifically phenolic compounds, among whichquercetin and ferulic acid stand out for their antioxidant activity. The main aim of this work hasbeen to study the technical feasibility of a combined ultrasound-assisted extraction (UAE) /nanofiltration (NF) process for the recovery of phenolic compounds present in wheat bran andonion skin wastes generated as by-products in local food companies.UAE was firstly performed for the extraction of polyphenols from wheat bran (WB) and onionskin waste (OSW) using an acetate buffer at pH 5 and an aqueous ethanol solution (70 vol.%) as solvents, respectively, under the optimum operating conditions. A final WB extract wasobtained with a total polyphenol content (TPC) of 3.56 ± 0.18 mg GAE/g WB and an antioxidantactivity (AA) of 7.75 ± 1.20 µmol Fe2+/g WB. An OSW extract was also obtained, with a TPC of44.47 ± 0.83 mg GAE/g OSW, a total flavonoid concentration (TFC) of 19.22 ± 0.35 mg QE/gOSW, and an AA of 28.38 ± 2.70 mg Trolox/g OSW. Ferulic acid is the main component ofwheat bran extract, while quercetin and its glycosylated derivatives are the main componentsof onion skin extract.Both extracts were then concentrated by nanofiltration (NF) in a high pressure stirred cell,using a NF270 flat polyamide membrane (270 Da cut-off), under optimal operating conditionsreaching a volume concentration ratio (VCR) of 5 after 7,5 and 1,8 h for WB and OSW extracts,respectively, with minimal loss of polyphenols in the permeates and recoveries of AA, TPC,and TFC in the concentrates higher than 99% in all cases.The results obtained in this study could contribute to the valorization of agri-food waste usingenvironmentally friendly techniques, demonstrating the potential o LK https://hdl.handle.net/10259/10870 UL https://hdl.handle.net/10259/10870 LA spa NO TED2021-129311B-I00 – Tecnologías verdes basadas en el empleo de fluidos presurizados para valorizar biomasa lignocelulósica mediante la producción de furfural (GREENFUR), financiado por el Ministerio de Ciencia e Innovación. PID2022-136385OB-I00 – Nuevas estrategias para la producción de ácido láctico de segunda generación empleando tecnologías emergentes basadas en fluidos presurizados (2BIOLAC), financiado por la Agencia Estatal de Investigación. BU027P23 – Tecnologías sostenibles de fluidos presurizados para valorizar subproductos de la industria agroalimentaria ricos en proteínas: nuevas estrategias, escalado y análisis tecnoeconómico y medioambiental (SOSPROTEIN), financiado por la Junta de Castilla y León y el Fondo Europeo de Desarrollo Regional (ERDF). DS Repositorio Institucional de la Universidad de Burgos RD 12-may-2026