RT info:eu-repo/semantics/bookPart
T1 Biosynthetic rules for marcrolide construction
A1 Aparicio Fernández, Jesús Manuel
A1 Mendes, Marta V.
A1 Antón Fidalgo, Nuria
A1 Martín Martín, Juan Francisco
K1 Microbiología
K1 Microbiology
K1 Bioquímica
K1 Biochemistry
AB Macrolides constitute a large class of naturalmetabolites produced by giant multifunctionalenzymes in a process resembling fatty acidbiosynthesis. Like f atty acids, macrolides and otherpolyketides are assernbled by decarboxylativecondensations of simple carboxylic acids. But whilefatty acid intermediates are fully reduced, macrolideand other polyketide intermediates suffer thesuppression of reduction or dehydration reactions atgiven biosynthetic steps. In the last years muchprogress has 'been made in our understanding of thelinear and modular organisation of the gene clusters,and the enzymes encoded by them, responsiblefor...
PB Research Signpost
SN 81-7736-113-9
YR 2002
FD 2002
LK https://hdl.handle.net/10259/11297
UL https://hdl.handle.net/10259/11297
LA eng
DS Repositorio Institucional de la Universidad de Burgos
RD 23-may-2026