RT info:eu-repo/semantics/article
T1 Antioxidant vitamin supplementation on muscle adaptations to resistance training: A double-blind, randomized controlled trial
A1 Martínez Ferrán, María
A1 Berlanga, Luis A.
A1 Barcelo-Guido, Olga
A1 Matos-Duarte, Michelle
A1 Vicente-Campos, Davinia
A1 Sánchez-Jorge, Sandra
A1 Romero-Morales, Carlos
A1 Munguía-Izquierdo, Diego
A1 Pareja-Galeano, Helios
K1 Ascorbic acid
K1 Vitamin C
K1 Vitamin E
K1 Dietary supplements
K1 Muscle strength
K1 Abdominal fat
K1 Entrenamiento con pesas
K1 Weight training
K1 Suplementos nutricionales
K1 Dietary supplements
AB Objectives:The aim of this study was to examine whether antioxidant vitamin supplementation with vitamin C (VitC) and vitamin E (VitE) affects the hypertrophic and functional adaptations to resistance training in trained men.Methods:This was a double-blind, randomized controlled trial in which participants were supplemented daily with VitC and VitE ( n = 12) or placebo ( n = 11) while completing a 10-wk resistance training program accompanied by a dietary intervention (300 kcal surplus and adequate protein intake) designed to optimize hypertrophy. Body composition (dual-energy x-ray absorptiometry), handgrip strength, and one-repetition maximum (1-RM), maximal force (F0), velocity (V0), and power (Pmax) were measured in bench press (BP) and squat (SQ) tests conducted before and after the intervention. To detect between-group differences, multiple-mixed analysis of variance, standardized differences, and qualitative differences were estimated. Relative changes within each group were assessed using a paired Student's t test.Results:In both groups, similar improvements were produced in BP 1-RM , SQ 1-RM SQ, and BP F0 (P < 0.05) after the resistance training program. A small effect size was observed for BP 1-RM (d = 0.53), BP F0 (d = 0.48), and SQ 1-RM (d = –0.39), but not for SQ F0 (d = 0.03). Dominant handgrip strength was significantly increased only in the placebo group (P < 0.05). According to body composition data, a significant increase was produced in upper body fat-free mass soft tissue (FFMST; P < 0.05) in the placebo group, whereas neither total nor segmental FFMST was increased in the vitamin group. Small intervention effect sizes were observed for upper body FFSMT (d = 0.32), non-dominant and dominant leg FFMST (d = –0.39; d = –0.42). Although a significant increase in total body fat was observed in both groups (P < 0.05) only the placebo group showed an increase in visceral adipose tissue (P < 0.05), showing a substantial intervention effect (d = 0.85).Conclusions:The data indicated that, although VitC/VitE supplementation seemed to blunt upper body strength and hypertrophy adaptations to resistance training, it could also mitigate gains in visceral adipose tissue elicited by an energy surplus.
PB Elsevier
SN 0899-9007
YR 2023
FD 2023-01
LK https://hdl.handle.net/10259/11329
UL https://hdl.handle.net/10259/11329
LA eng
DS Repositorio Institucional de la Universidad de Burgos
RD 03-jun-2026