RT info:eu-repo/semantics/article
T1 Ten millennia of hepatitis B virus evolution
A1 Kocher, Arthur
A1 Papac, Luka
A1 Barquera, Rodrigo
A1 Key, Felix M.
A1 Spyrou, Maria A.
A1 Hübler, Ron
A1 Rohrlach, Adam B.
A1 Aron, Franziska
A1 Stahl, Raphaela
A1 Wissgott, Antje
A1 van Bömmel, Florian
A1 Pfefferkorn, Maria
A1 Mittnik, Alissa
A1 Villalba-Mouco, Vanessa
A1 Neumann, Gunnar U.
A1 Rivollat, Maïté
A1 van de Loosdrecht, Marieke S.
A1 Majander, Kerttu
A1 Tukhbatova, Rezeda I.
A1 Musralina, Lyazzat
A1 Ghalichi, Ayshin
A1 Penske, Sandra
A1 Sabin, Susanna
A1 Michel, Megan
A1 Gretzinger, Joscha
A1 Nelson, Elizabeth A.
A1 Ferraz, Tiago
A1 Nägele, Kathrin
A1 Parker, Cody
A1 Keller, Marcel
A1 Guevara, Evelyn K.
A1 Feldman, Michal
A1 Eisenmann, Stefanie
A1 Skourtanioti, Eirini
A1 Giffin, Karen
A1 Gnecchi-Ruscone, Guido Alberto
A1 Friederich, Susanne
A1 Schimmenti, Vittoria
A1 Khartanovich, Valery
A1 Karapetian, Marina K.
A1 Chaplygin, Mikhail S.
A1 Kufterin, Vladimir V.
A1 Khokhlov, Aleksandr A.
A1 Chizhevsky, Andrey A.
A1 Stashenkov, Dmitry A.
A1 Kochkina, Anna F.
A1 Tejedor-Rodríguez, Cristina
A1 de Lagrán, Íñigo García-Martínez
A1 Arcusa-Magallón, Héctor
A1 Garrido-Pena, Rafael
A1 Royo-Guillén, José Ignacio
A1 Nováček, Jan
A1 Rottier, Stéphane
A1 Kacki, Sacha
A1 Saintot, Sylvie
A1 Kaverzneva, Elena
A1 Belinskiy, Andrej B.
A1 Velemínský, Petr
A1 Limburský, Petr
A1 Kostka, Michal
A1 Loe, Louise
A1 Popescu, Elizabeth
A1 Clarke, Rachel
A1 Lyons, Alice
A1 Mortimer, Richard
A1 Sajantila, Antti
A1 de Armas, Yadira Chinique
A1 Hernandez Godoy, Silvia Teresita
A1 Hernández-Zaragoza, Diana I.
A1 Pearson, Jessica
A1 Binder, Didier
A1 Lefranc, Philippe
A1 Kantorovich, Anatoly R.
A1 Maslov, Vladimir E.
A1 Lai, Luca
A1 Zoledziewska, Magdalena
A1 Beckett, Jessica F.
A1 Langová, Michaela
A1 Danielisová, Alžběta
A1 Ingman, Tara
A1 Atiénzar, Gabriel García
A1 de Miguel Ibáñez, Maria Paz
A1 Romero, Alejandro
A1 Sperduti, Alessandra
A1 Beckett, Sophie
A1 Salter, Susannah J.
A1 Zilivinskaya, Emma D.
A1 Vasil’ev, Dmitry V.
A1 von Heyking, Kristin
A1 Burger, Richard L.
A1 Salazar, Lucy C.
A1 Amkreutz, Luc
A1 Navruzbekov, Masnav
A1 Rosenstock, Eva
A1 Alonso-Fernández, Carmen
A1 Slavchev, Vladimir
A1 Kalmykov, Alexey A.
A1 Atabiev, Biaslan Ch.
A1 Batieva, Elena
A1 Calmet, Micaela Alvarez
A1 Llamas, Bastien
A1 Schultz, Michael
A1 Krauß, Raiko
A1 Jiménez-Echevarría, Javier
A1 Francken, Michael
A1 Shnaider, Svetlana
A1 de Knijff, Peter
A1 Altena, Eveline
A1 Van de Vijver, Katrien
A1 Fehren-Schmitz, Lars
A1 Tung, Tiffiny A.
A1 Lösch, Sandra
A1 Dobrovolskaya, Maria
A1 Makarov, Nikolaj
A1 Read, Chris
A1 Van Twest, Melanie
A1 Sagona, Claudia
A1 Ramsl, Peter C.
A1 Akar, Murat
A1 Yener, K. Aslihan
A1 Carmona Ballestero, Eduardo
A1 Cucca, Francesco
A1 Mazzarello, Vittorio
A1 Utrilla, Pilar
A1 Rademaker, Kurt
A1 Fernández-Domínguez, Eva
A1 Baird, Douglas
A1 Semal, Patrick
A1 Márquez-Morfín, Lourdes
A1 Roksandic, Mirjana
A1 Steiner, Hubert
A1 Salazar-García, Domingo Carlos
A1 Shishlina, Natalia
A1 Erdal, Yilmaz Selim
A1 Hallgren, Fredrik
A1 Boyadzhiev, Yavor
A1 Boyadzhiev, Kamen
A1 Küßner, Mario
A1 Sayer, Duncan
A1 Onkamo, Päivi
A1 Skeates, Robin
A1 Rojo-Guerra, Manuel
A1 Buzhilova, Alexandra
A1 Khussainova, Elmira
A1 Djansugurova, Leyla B.
A1 Beisenov, Arman Z.
A1 Samashev, Zainolla
A1 Massy, Ken
A1 Mannino, Marcello
A1 Moiseyev, Vyacheslav
A1 Mannermaa, Kristiina
A1 Balanovsky, Oleg
A1 Deguilloux, Marie-France
A1 Reinhold, Sabine
A1 Hansen, Svend
A1 Kitov, Egor P.
A1 Dobeš, Miroslav
A1 Ernée, Michal
A1 Meller, Harald
A1 Alt, Kurt W.
A1 Prüfer, Kay
A1 Warinner, Christina
A1 Schiffels, Stephan
A1 Stockhammer, Philipp W.
A1 Bos, Kirsten
A1 Posth, Cosimo
A1 Herbig, Alexander
A1 Haak, Wolfgang
A1 Krause, Johannes
A1 Kühnert, Denise
K1 Hepatitis B
K1 Genética de poblaciones
K1 Population genetics
AB Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd millennium BCE. The only remnant of this prehistoric HBV diversity is the rare genotype G, which appears to have reemerged during the HIV pandemic.
PB American Association for the Advancement of Science
SN 0036-8075
YR 2021
FD 2021-10
LK https://hdl.handle.net/10259/11467
UL https://hdl.handle.net/10259/11467
LA eng
NO The research was funded by the Max Planck Society, the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (771234–PALEoRIDER, to W.H.; 805268–CoDisEASe to K. Bos; 834616–ARCHCAUCASUS to S.H.), the Slovak Academy of Sciences and the European Union’s Seventh Framework Programme and Marie Curie Actions under the Programme SASPRO (1340/03/03 to P.C.R.), the ERA.NET RUS Plus–S&T programm of the European Union’s Seventh Framework Programme (277–BIOARCCAUCASUS to S.Re. and S.H.), the Werner Siemens Stiftung (“Paleobiochemistry”, to CW), the Award Praemium Academiae of the Czech Academy of Sciences (to M.E.), the Institute of Archaeology of the Czech Academy of Sciences (RVO 67985912, to M.Dobe.), the Russian Foundation for Basic Research (19-09-00354a, to M.K.K. and V.V.K.; 19-78-10053 to SSh), the German Research Foundation (DFG-HA-5407/4-1–INTERACT to W.H. and RE2688/2 to S.Re.), the French National Research Agency (ANR-17-FRAL-0010–INTERACT, to M.F.D., M.Ri., S.Ro., S.Sai., D.Bi., and P.Le.), the Wenner-Gren Dissertation Fieldwork Grant (9558 to S.Sab.), and the Ministry of Education and Science of the Republic of Kazakhstan (AP08856654 to L.B.D., L.M., and E.Kh. and AP08857177 to A.Z.B.).
DS Repositorio Institucional de la Universidad de Burgos
RD 17-abr-2026