RT info:eu-repo/semantics/article
T1 Methods and tools for the safety assessment part of the European Commission’s safe and sustainable by design framework when applied to advanced materials
A1 Pomar-Portillo, Vicenç
A1 Suarez-Merino, Blanca
A1 Aparicio Martínez, Santiago
A1 Badetti, Elena
A1 Boyles, Mathew
A1 Brunelli, Andrea
A1 Fito-López, Carlos
A1 Garmendia-Aguirre, Irantzu
A1 Giubilato, Elisa
A1 Katsumiti, Alberto
A1 Laurini, Erik
A1 Lofty, Morgan
A1 Marson, Domenico
A1 Pizzol, Lisa
A1 Rodríguez-Llopis, Isabel
A1 Rumbo Lorenzo, Carlos
A1 Scott-Fordsmand, Janeck J.
A1 Stone, Vicki
A1 Trabucco, Sara
A1 Hristozov, Danail
A1 Nowack, Bernd
K1 SSbD
K1 Safe and sustainable by design
K1 Advanced materials
K1 Hazard assessment
K1 Risk assessment
K1 Computational tools
K1 Evaluación del riesgo
K1 Risk assessment
AB The Safe and Sustainable-by-Design (SSbD) framework by the EC-JRC (European Commission – Joint ResearchCentre) provides a structured approach to integrate safety and sustainability considerations from the earlieststages of chemical and material innovation. However, applying SSbD principles to advanced materials posesspecific challenges due to their complex and diverse physicochemical properties. This work analyzes and mapshazard, exposure, fate and risk assessment methods and tools applicable to Steps 1, 2 and 3 of the EC-JRC SSbDframework, categorizing them across its three tiers to address different stages of product development. Theanalysis highlights the challenges of adapting conventional testing and modelling approaches to advanced materials, particularly for hazard assessment, and considers the relevance and limitations of tools originallydeveloped for exposure and risk assessment of engineered nanomaterials when applied to broader advancedmaterials categories. An assessment of operational status, access conditions, and tool formats provides practicalinsights for researchers and industry stakeholders. The study identifies key methodological gaps and offersrecommendations to improve and expand the current tool landscape. By providing a structured mapping ofavailable resources and challenges, this work supports the effective implementation of SSbD principles, promoting the safe and sustainable development of advanced materials
PB Elsevier
SN 0160-4120
YR 2025
FD 2025-11
LK https://hdl.handle.net/10259/11718
UL https://hdl.handle.net/10259/11718
LA eng
NO Funding for this research was received from the European Union (EU) Horizon Europe project SUNRISE (Grant agreement number – 101137324 and the Swiss State Secretariat for Education, Research and Innovation (SERI) no 23.00563)
DS Repositorio Institucional de la Universidad de Burgos
RD 26-may-2026