Ponencias / Comunicaciones de congresos ICCRAM-ESThttps://hdl.handle.net/10259/122362026-10-29T10:21:01Z2026-10-29T10:21:01ZDevelopment of a methodology to perform toxicokinetics and toxicodynamics studies in biofilmsRumbo Lorenzo, CarlosCollado, SaraGonzález Plaza, Juan JoséFuente Vivas, Dalia de laFernández Pampín, NataliaBaccaro, MartaVan den Brink, Nico W.Barros García, RocíoMartel Martín, SoniaTamayo Ramos, Juan Antoniohttps://hdl.handle.net/10259/122942026-10-23T00:05:38Z2022-01-01T00:00:00ZDevelopment of a methodology to perform toxicokinetics and toxicodynamics studies in biofilms
Rumbo Lorenzo, Carlos; Collado, Sara; González Plaza, Juan José; Fuente Vivas, Dalia de la; Fernández Pampín, Natalia; Baccaro, Marta; Van den Brink, Nico W.; Barros García, Rocío; Martel Martín, Sonia; Tamayo Ramos, Juan Antonio
Environmental research has focussed on elucidating and modelling of
toxicokinetics and toxicodynamics of different types of nanomaterials in soil
and aquatic organisms, and also in biofilms.
The first steps towards the developing of a protocol to analyse Multi Component NanoMaterials (MCNMs) and High Aspect Ratio Nanoparticles
(HARNs) tokicokinetics and toxicodynamics in biofilms are described here,
using P. putida as model organism.
Póster presentado en: 21º Congreso Internacional de la European Society of Toxicology In Vitro (ESTIV 2022), 21 al 25 de noviembre de 2022 en Barcelona-Sitges, España
2022-01-01T00:00:00ZDesarrollo de una metodología para evaluar el impacto toxicológico de nuevos nanomateriales sobre biofilms bacterianosFuente Vivas, Dalia de laCollado, SaraFernández Pampín, NataliaDasgupta, NanditaGómez Cuadrado, LauraBarros García, RocíoMartel Martín, SoniaRumbo Lorenzo, Carloshttps://hdl.handle.net/10259/122932026-10-23T00:05:32Z2023-01-01T00:00:00ZDesarrollo de una metodología para evaluar el impacto toxicológico de nuevos nanomateriales sobre biofilms bacterianos
Fuente Vivas, Dalia de la; Collado, Sara; Fernández Pampín, Natalia; Dasgupta, Nandita; Gómez Cuadrado, Laura; Barros García, Rocío; Martel Martín, Sonia; Rumbo Lorenzo, Carlos
Durante los últimos años, el incremento del uso de
nanopartículas (NP) en diversos ámbitos, como medicina o
agricultura, despierta la necesidad de evaluar el riesgo que
suponen para la salud y el medio ambiente. En este sentido, los
biofilms se consideran excelentes candidatos para ser utilizados
en estudios de eco-toxicidad, por su capacidad para acumular y
responder rápidamente a xenobióticos. Sin embargo, no existe
un protocolo estandarizado, habiendo únicamente un artículo
publicado al respecto (Chaumet et al., 2019).
Este trabajo aborda el desarrollo de una metodología para la
ejecución de estudios de toxicocinética y toxicodinámica en
biofilms formados por Pseudomonas putida tratados con
nanopartículas (NP) de ZnO:Mn.
Póster presentado en: XXIX Congreso de la Sociedad Española de Microbiología (SEM 2023), Universidad de Burgos, 25 al 28 de junio de 2023
2023-01-01T00:00:00ZThe Role of Dynamic 3D Models in Evaluating MXenes Toxicity: A Focus on Pulmonary and Hepatic CellsFuente Vivas, Dalia de laParra de la Parra, Sandra de laSendra Vega, MartaRumbo Lorenzo, CarlosMartel Martín, SoniaBarros García, RocíoGómez Cuadrado, Laurahttps://hdl.handle.net/10259/122532026-10-09T00:05:42Z2025-01-01T00:00:00ZThe Role of Dynamic 3D Models in Evaluating MXenes Toxicity: A Focus on Pulmonary and Hepatic Cells
Fuente Vivas, Dalia de la; Parra de la Parra, Sandra de la; Sendra Vega, Marta; Rumbo Lorenzo, Carlos; Martel Martín, Sonia; Barros García, Rocío; Gómez Cuadrado, Laura
Background: MXenes and Graphene possess outstanding physicochemical properties.
They have strong application potential in electronics, energy storage, and
biomedicine.
Challenge: Current nanoparticle regulations present critical gaps, particularly in human
health risk assessment. There is a growing need for Safe and Sustainable by
Design (SSbD) aligned evaluation strategies.
Aim: To bridge the in vitro–in vivo gap in nanosafety research.
Approach: Advanced in vitro models, including static and dynamic 3D cellular systems,
were applied and compared to conventional 2D cultures.
Impact: These methodologies offer promising tools for improving the hazard
assessment of 2D-nanomaterials, such as MXenes.
Póster presentado en: 59th Congress of the European Societies of Toxicology (EUROTOX 2025) "Toxicology addresses society's real life risks for sustainable health and well being", 14-17 September 2025, Athens, Greece
2025-01-01T00:00:00ZPEST-PD:The Pathto Early Parkinson´s Detection Preliminary Findings from an Ongoing Longitudinal Observational Study for Prodromal Parkinson’s disease in farmers exposed to pesticidesGómez Cuadrado, LauraGarcía García, DavidCanepa Oneto, Antonio JesúsLara, Daniel deAlonso Núñez, BelénLópez Marín, SofíaFuente Vivas, Dalia de laVillanueva Alameda, María IsabelBarros García, RocíoAparicio Martínez, SantiagoRodríguez Diez, Juan JoséLópez Nozal, CarlosRamírez Sanz, José MiguelGómez-Gregoris, IreneCatón, BeatrizDíaz Hurtado, JorgeCalvo Simal, SaraTrigo, JavierSánchez, JavierLisei, DaríoOlalla Gallo, Mª ÁngelesAllende del Río, MartaRivadeneyra Posadas, Jéssica JannettBegum, Bacinoglu MerveModa, FabioCubo Delgado, Estherhttps://hdl.handle.net/10259/122502026-10-09T00:05:34Z2026-01-01T00:00:00ZPEST-PD:The Pathto Early Parkinson´s Detection Preliminary Findings from an Ongoing Longitudinal Observational Study for Prodromal Parkinson’s disease in farmers exposed to pesticides
Gómez Cuadrado, Laura; García García, David; Canepa Oneto, Antonio Jesús; Lara, Daniel de; Alonso Núñez, Belén; López Marín, Sofía; Fuente Vivas, Dalia de la; Villanueva Alameda, María Isabel; Barros García, Rocío; Aparicio Martínez, Santiago; Rodríguez Diez, Juan José; López Nozal, Carlos; Ramírez Sanz, José Miguel; Gómez-Gregoris, Irene; Catón, Beatriz; Díaz Hurtado, Jorge; Calvo Simal, Sara; Trigo, Javier; Sánchez, Javier; Lisei, Darío; Olalla Gallo, Mª Ángeles; Allende del Río, Marta; Rivadeneyra Posadas, Jéssica Jannett; Begum, Bacinoglu Merve; Moda, Fabio; Cubo Delgado, Esther
PEST-PD is a multi-center project that brings together a multidisciplinary research team composed of neurologists, primary care physicians,
physicians specialized in Clinical Analysis and Nuclear Medicine, radiophysicists, biotechnologists, biologists, biostatisticians, agricultural-,
telecommunications- and health- engineers, with the aim to understand different aspects of the prevalence of preclinical and prodromal PD in
subjects exposed and not exposed to pesticides
Póster presentado en: International Congress of Parkinson’s Disease and Movement Disorders, Seoul, Korea, October 4-8, 2026
2026-01-01T00:00:00Z