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    Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10259.4/2523

    Título
    Role of oleic acid in immune system; mechanism of action; a review
    Otro título
    Papel del ácido oleico en el sistema inmune: mecanismos de acción: revisión científica
    Autor
    Carrillo Pérez, CeliaAutoridad UBU
    Cavia Camarero, María del MarAutoridad UBU
    Alonso de la Torre, SaraAutoridad UBU
    Publicado en
    Nutrición Hospitalaria, 2012, v.27, n.4 (julio-agosto), p. 978-990
    Editorial
    Grupo Aula Médica
    Fecha de publicación
    2012
    ISSN
    0212-1611
    DOI
    10.3305/nh.2012.27.4.5783
    Abstract
    Introduction:Although n-3 polyunsaturated fatty acids have been widely described as antiinflammatory fats, little is known about the role of oleic acid in immune system. Aim: The aim of the present review is to join all the reports available in order to analyze where exactly the knowledge concerning this topic is and what the causes of the controversial data could be. Methods: We searched electronic databases and bibliographies of selected articles were inspected for further reference. Results:Diets rich in oleic acid have beneficial effects in inflammatory-related diseases. In addition, a wide range of studies evaluate the effect of oleic acid in different cellular functions thus reporting a potential mechanism for the biological effect of such a fat. However, some controversial data can be found in literature, maybe related to the kind of study or even the dose of the reagent added. Conclusion:In conclusion, oleic acid could be reported as an anti-inflammatory fatty acid playing a role in the activation of different pathways of immune competent cells.
    Palabras clave
    Ácido oleico
    Sistema inmune
    Señalización celular
    Oleic acid
    Immune system
    Intracellular signaling
    Materia
    Biología molecular
    Molecular biology
    URI
    http://hdl.handle.net/10259.4/2523
    Versión del editor
    http://dx.doi.org/10.3305%2Fnh.2012.27.4.5783
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    • Artículos NUTRICION
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