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dc.contributor.advisorDomínguez Renedo, Olga 
dc.contributor.authorSancho Querol, Sara
dc.contributor.otherUniversidad de Burgos. Departamento de Química
dc.date.accessioned2014-10-21T10:06:26Z
dc.date.available2014-10-21T10:06:26Z
dc.date.submitted2014
dc.identifier.urihttp://hdl.handle.net/10259/3533
dc.description.abstractThis work reports the development of two different sensors using screen-printed carbon electrodes (SPCEs) for the determination of imipramine (IMP) by differential pulse voltammetry. On one hand, a bare SPCE has been successfully applied to the determination of this compound and, on the other hand, the modification of this SPCE with metallic gold nanoparticles (AuNPs/SPCE) have led to an increase in the sensitivity of IMP determination. Both sensors have been characterized obtaining good capability of detection (14.1 μM and 0.28 μM for SPCE and AuNPs/SPCE, respectively) and reproducibility (4.75 % and 6.87 % for SPCE and AuNPs/SPCE, respectively) values. The specificity of both sensors towards different compounds has been also analyzed and, the developed electrochemical systems have been successfully applied in the determination of IMP in commercial pharmaceutical preparations.en
dc.format.mimetypeapplication/pdf
dc.language.isospaes
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.otherQuímica analíticaes
dc.subject.otherChemistry, Analyticen
dc.titlePuesta a punto de un biosensor para la determinación de analitos de interés en el tratamiento de trastornos depresivos: detección electroquímica de imipramina
dc.typeTrabajo fin de gradoes
dc.typeinfo:eu-repo/semantics/bachelorThesis
dc.rights.holderEste documento está sujeto a una licencia de uso Creative Commons, por la cual está permitido hacer copia, distribuir y comunicar públicamente la obra siempre que se cite al autor original y no se haga de él uso comercial ni obra derivada


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