2026-04-17T12:22:37Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/101932025-07-28T11:57:58Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845

New screen-printed electrodes for Raman spectroelectrochemistry. Determination of p-aminosalicylic acid Romay García, Luis Núñez Marinero, Pello Perales Rondon, Juan Víctor Heras Vidaurre, Aránzazu Campo García, Francisco Javier del Colina Santamaría, Álvaro Screen-printed electrodes Raman spectroelectrochemistry Electrochemistry EC-SERS EC-SOERS 4-Aminosalicylic acid Química analítica Electroquímica Chemistry, Analytic Electrochemistry The availability of new surface enhanced Raman scattering (SERS) substrates is essential to develop quantitative analytical methods. Electrochemistry is an easy, fast and reproducible methodology to prepare SERS substrates on screen-printed electrodes (SPEs). Results: This work proposes new SPEs based on a three-electrode system all made of silver. Using the same ink for the whole electrode system facilitates the fabrication process, reduces production costs, and leads to excellent analytical performance. The results showed that Raman enhancement depends strongly on the type of silver ink. To demonstrate the capabilities of the new electrodes developed, 4-aminosalicylic acid was determined in complex matrices and in the presence of strong interfering compounds such as salicylic acid and acetylsalicylic acid. The proposed analytical method is based on the electrochemical surface oxidation enhanced Raman scat tering (EC-SOERS) strategy. AgCl nanocrystals are generated on the working electrode surface, which amplify the Raman signal of 4-aminosalicylic acid. Good figures of merit were obtained both in the absence and in the presence of the interfering compounds, achieving a correct estimation of a 4-aminosalicylic test sample in complex matrices. Significance: The new SPEs have been demonstrated to be very sensitive and reproducible which, together to the high specificity of the Raman signal, makes this methodology very attractive for chemical analysis. Ministerio de Ciencia e Innovacion ´ and Agencia Estatal de Inves tigacion ´ (MCIN/AEI/10.13039/501100011033, PID2020-113154RBC21, PID2020-113154RB-C22), Junta de Castilla y Leon ´ and European Regional Development Fund (Grant number: BU036P23), Ministerio de Ciencia, Innovacion ´ y Universidades (RED2022-134120-T) are grate fully acknowledged for funding this work. L.R. acknowledges Ministerio de Ciencia e Innovacion ´ and Agencia Estatal de Investigacion ´ (MCIN/ AEI/10.13039/501100011033, PIS2020-113154 GB-C21) for the pre doctoral contract. 2025-02-10T09:21:00Z 2025-02-10T09:21:00Z 2024-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 0003-2670 http://hdl.handle.net/10259/10193 10.1016/j.aca.2024.343095 eng Analytica Chimica Acta. 2024, V. 1325, p. 343095 https://doi.org/10.1016/j.aca.2024.343095 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2017-2020/PID2020-113154RB-C21/ES/APLICACION DE NUEVOS MATERIALES Y DISPOSITIVOS PARA EC-SERS Y EC-SOERS/ info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2017-2020/PID2020-113154RB-C22/ES/DESARROLLO DE NUEVOS MATERIALES Y DISPOSITIVOS PARA EC-SERS y EC-SOERS/ info:eu-repo/grantAgreement/Junta de Castilla y León//BU036P23//Desarrollo de técnicas analíticas in-situ y en condiciones operando para el estudio de electrocatalizadores para la conversión electroquímica de nitrato de amoniaco/ info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2021-2023/RED2022-134120-T/ES/RED DE SENSORES Y BIOSENSORES ELECTROQUIMICOS: RETOS ANTE LA TRANSFORMACION DIGITAL E INDUSTRIAL/ Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess application/pdf Elsevier