2026-09-16T12:22:10Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/105002025-05-28T00:05:23Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594

00925njm 22002777a 4500 dc Muñoz Torres, Miguel Ángel author Suárez Pantiga, Samuel author Sanz Díez, Roberto author 2024-06 A series of pyrrol-yn-glycol derivatives were easily prepared from simple pyrroles through a three-step sequence involving hydroxyalkylation-alkynylation-O-silylation. Their reaction with IPrAuNTf2 triggers a C2-pyrrole attack onto the activated alkyne and subsequent highly selective 1,2-migration of the oxyalkyl group in the intermediate spirocycle. This approach enables the efficient synthesis of a wide selection of regioselectively functionalized 4-hydroxyindoles, which represent important yet challenging indole scaffolds, in high yields. 1523-7060 http://hdl.handle.net/10259/10500 10.1021/acs.orglett.4c01581 1523-7052 Gold-Catalyzed “Back-to-Front” Synthesis of 4-Silyloxyindoles