2026-09-08T06:53:02Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/105022025-05-28T00:05:24Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594

00925njm 22002777a 4500 dc Gómez Gil, Sara author Cases, Nuria author Hernández Ruiz, Raquel author Rubio Presa, Rubén author Suárez Pantiga, Samuel author Pedrosa Sáez, María de los Remedios author Sanz Díez, Roberto author 2024-03 We report the efficient, sustainable one-pot synthesis of a wide variety of N-polyheterocycles, such as imidazo-quinolines and quinoxalines, and furoquinolines, from easily available nitroaromatics and glycols via a molybdenum catalytic domino reduction-imine formation-intramolecular cyclization-oxidation sequence. It is worth highlighting that the recycling and incorporation of the waste carbonyl byproduct, generated in the reduction step, into the final compound is realized. In addition, the overall efficiency and atom economy of the process are further improved owing to the participation of one reaction intermediate as reductant that allows lowering the amount of external reducing agent employed. 1434-193X http://hdl.handle.net/10259/10502 10.1002/ejoc.202400145 1099-0690 Molybdenum‐Catalyzed One‐Pot Multi‐Step Synthesis of N‐Polyheterocycles from Nitroarenes and Glycols