2026-06-18T03:32:33Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/105022025-05-28T00:05:24Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594
Repositorio Institucional de la Universidad de Burgos
author
Gómez Gil, Sara
author
Cases, Nuria
author
Hernández Ruiz, Raquel
author
Rubio Presa, Rubén
author
Suárez Pantiga, Samuel
author
Pedrosa Sáez, María de los Remedios
author
Sanz Díez, Roberto
2025-05-27T12:23:29Z
2025-05-27T12:23:29Z
2024-03
1434-193X
http://hdl.handle.net/10259/10502
10.1002/ejoc.202400145
1099-0690
We report the efficient, sustainable one-pot synthesis of a wide variety of N-polyheterocycles, such as imidazo-quinolines and quinoxalines, and furoquinolines, from easily available nitroaromatics and glycols via a molybdenum catalytic domino reduction-imine formation-intramolecular cyclization-oxidation sequence. It is worth highlighting that the recycling and incorporation of the waste carbonyl byproduct, generated in the reduction step, into the final compound is realized. In addition, the overall efficiency and atom economy of the process are further improved owing to the participation of one reaction intermediate as reductant that allows lowering the amount of external reducing agent employed.
eng
Atribución-NoComercial 4.0 Internacional
Molybdenum‐Catalyzed One‐Pot Multi‐Step Synthesis of N‐Polyheterocycles from Nitroarenes and Glycols
info:eu-repo/semantics/article
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URL
https://riubu.ubu.es/bitstream/10259/10502/1/G%c3%b3mez-ejooc_2024.pdf
File
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6dc1f41fc9a16264caebb6243cb014ae
3616578
application/pdf
Gómez-ejooc_2024.pdf