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00925njm 22002777a 4500 dc Flieh, S.M. author Miguel Berges, M.L. author Huybrechts, I. author Castillo, M.J. author Gonzalez Gross, M. author Marcos, A. author Gottrand, F. author Le Donne, C. author Widhalm, K. author Molnár, Denes author Stehle, P. author Kafatos, A. author Dallongeville, J. author Gesteiro, E. author Abbeddou, S. author Moreno, L.A. author González-Gil, E.M. author Coordinator, null author Core Group members, null author De Henauw, S. author González-Gross, M. author Gilbert, C. author Steering Committee, null author Libersa, C. author Castelló, S. author Kersting, M. author Sjöstrom, M. author Hall, G. author Maes, L. author Scalfi, L. author Project Manager, null author Meléndez, P. author Casajús, J.A. author Fleta, J. author Rodríguez, G. author Tomás, C. author Mesana, M.I. author Vicente-Rodríguez, G. author Villarroya, A. author Gil, C.M. author Ara, I. author Alvira, J.F. author Bueno, G. author Bueno, O. author León, J.F. author Garagorri, J.Ma author Labayen, I. author Iglesia, I. author Bel, S. author Gracia Marco, L.A. author Mouratidou, T. author Santaliestra-Pasías, A. author González-Gil, E. author De Miguel-Etayo, P. author Miguel-Berges, M. author Iguacel, I. author Rupérez, A. author Wärnberg, J. author Nova, E. author Gómez, S. author Díaz, L.E. author Romeo, J. author Veses, A. author Zapatera, B. author Pozo, T. author Martínez, D. author Beghin, L. author Iliescu, C. author Von Berlepsch, J. author Sichert-Hellert, W. author Koeppen, E. author Molnar, D. author Erhardt, E. author Csernus, K. author Török, K. author Bokor, S. author Angster, M. author Nagy, E.ö author Kovács, O. author Répasi, J. author Codrington, C. author Plada, M. author Papadaki, A. author Sarri, K. author Viskadourou, A. author Hatzis, C. author Kiriakakis, M. author Tsibinos, G. author Vardavas, C. author Sbokos, M. author Protoyeraki, E. author Fasoulaki, M. author Pietrzik, K. author Breidenassel, C. author Spinneker, A. author Al-Tahan, J. author Segoviano, M. author Berchtold, A. author Bierschbach, C. author Blatzheim, E. author Schuch, A. author Pickert, P. author Gutiérrez, Á. author Ortega, F.B. author Ruiz, J.R. author Artero, E.G. author España, V. author Jiménez-Pavón, D. author Chillón, P. author Sánchez-Muñoz, C. author Cuenca, M. author former INRAN, null author Arcella, D. author Azzini, E. author Barrison, E. author Bevilacqua, N. author Buonocore, P. author Catasta, G. author Censi, L. author Ciarapica, D. author D'Acapito, P. author Ferrari, M. author Galfo, M. author Leclercq, C. author Maiani, G. author Mauro, B. author Mistura, L. author Pasquali, A. author Piccinelli, R. author Polito, A. author Roccaldo, R. author Spada, R. author Sette, S. author Zaccaria, M. author Vitaglione, P. author Montagnese, C. author De Bourdeaudhuij, I. author De Vriendt, T. author Matthys, C. author Vereecken, C. author de Maeyer, M. author Ottevaere, C. author Phillipp, K. author Dietrich, S. author Kubelka, B. author Boriss-Riedl, M. author Manios, Y. author Grammatikaki, E. author Bouloubasi, Z. author Cook, T.L. author Eleutheriou, S. author Consta, O. author Moschonis, G. author Katsaroli, I. author Kraniou, G. author Papoutsou, S. author Keke, D. author Petraki, I. author Bellou, E. author Tanagra, S. author Kallianoti, K. author Argyropoulou, D. author Tsikrika, S. author Karaiskos, C. author Meirhaeghe, A. author Hagströmer, M. author Wennlöf, A.H. author Hallström, L. author Patterson, E. author Kwak, L. author Rizzo, N. author Sánchez-Molero, J. author Picó, E. author Navarro, M. author Viadel, B. author Carreres, J.E. author Merino, G. author Sanjuán, R. author Lorente, M. author Sánchez, M.J. author Thoma-IRs, S. author Allchurch, E. author Burgess, P. author Astrom, A. author Sverkén, A. author Broberg, A. author Masson, A. author Lehoux, C. author Brabant, P. author Pate, P. author Fontaine, L. author Sebok, A. author Kuti, T. author Hegyi, A. author Maldonado, C. author Llorente, A. author García, E. author von Fircks, H. author Hallberg, M.L. author Messerer, M. author Larsson, M. author Fredriksson, H. author Adamsson, V. author Börjesson, I. author Fernández, L. author Smillie, L. author Wills, J. author Pedrero-Chamizo, R. author Meléndez, A. author Valtueña, J. author Albers, U. author Benito, P.J. author Gómez Lorente, J.J. author Cañada, D. author Urzanqui, A. author Torres, R.M. author Navarro, P. author 2022-05 Background and aims This study aims to examine the associations of food portion size (PS) with markers of insulin resistance (IR) and clustered of metabolic risk score in European adolescents. Methods A total of 495 adolescents (53.5% females) from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study were included. The association between PS from food groups and homeostasis model assessment of insulin resistance (HOMA-IR) index, VO2 max, and metabolic risk score was assessed by multilinear regression analysis adjusting for several confounders. Analysis of covariance (ANCOVA) was used to determine the mean differences of food PS from food groups by HOMA-IR cutoff categories by using maternal education as a covariable. Results Larger PS from vegetables in both gender and milk, yoghurt, and milk beverages in males were associated with higher VO2 max, while larger PS from margarines and vegetable oils were associated with lower VO2 max (p < 0.05). Males who consumed larger PS from fish and fish products; meat substitutes, nuts, and pulses; cakes, pies, and biscuits; and sugar, honey, jams, and chocolate have a higher metabolic risk score (p < 0.05). Males with lower HOMA-IR cutoff values consumed larger PS from vegetables, milk, yoghurt, and milk beverages (p < 0.05). Females with lower HOMA-IR cutoff values consumed larger PS from breakfast cereals, while those with higher HOMA-IR cutoff values consumed larger PS from butter and animal fats (p = 0.018). Conclusion The results show that larger PS from dairy products, cereals, and high energy dense foods are a significant determinant of IR and VO2 max, and larger PS from food with higher content of sugar were associated with higher metabolic risk score. 0939-4753 https://hdl.handle.net/10259/12086 10.1016/J.NUMECD.2022.05.017 Food portion size (PS) VO2 max Insulin resistance (IR) Metabolic syndrome (MS) Adolescents Associations between food portion sizes, insulin resistance, VO2 max and metabolic syndrome in European adolescents: The HELENA study