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<dc:title>Exploring Sex Activity Impact on Biological Biomarkers and Athletic Parameters in Sexually and Physically Active Healthy Adults: A Systematic Review of Clinical Trials</dc:title>
<dc:creator>Fernández Lázaro, Diego</dc:creator>
<dc:creator>Seco Calvo, Jesús</dc:creator>
<dc:creator>Izquierdo, José María</dc:creator>
<dc:creator>Mielgo Ayuso, Juan</dc:creator>
<dc:creator>Roche, Enrique</dc:creator>
<dc:creator>Santamaría, Gema</dc:creator>
<dc:subject>Abstinence</dc:subject>
<dc:subject>Hormones</dc:subject>
<dc:subject>Perceptual parameters</dc:subject>
<dc:subject>Biomarkers sexual activity</dc:subject>
<dc:subject>Sports performance</dc:subject>
<dc:subject>Systematic review</dc:subject>
<dc:description>Background: A sexually active lifestyle is generally associated with positive effects on physical condition and health. However, engaging in sexual activity prior to a sports competition could affect athletic performance. This systematic review examines the current literature on the impact of pre-exercise sexual activity on sports performance, with particular attention paid to its effects on physiological, hormonal, cognitive, and perceptual markers. Method: Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we systematically reviewed original studies published within the last 25 years. Eligible studies were randomized or non-randomized controlled design and indexed on PubMed, Scopus, Dialnet, and Cochrane. Additional sources were consulted including a network diagram with Connected Papers®. Two methodological quality scales, McMaster University Occupational Therapy Evidence-Based Practice Research Group and Physiotherapy Evidence Database (PEDro), were used. The study was registered in PROSPERO (#CRD42023426555). Results: A total of 244 records were identified through the search process, of which 7 studies met the inclusion criteria. The studies involved 117 (115 men) physically and sexually active subjects including 29 elite top athletes. When comparing the sexual activity condition/group (SexG) to abstinence (AbsG), significant (p &lt; 0.05) decreases were observed in average speed and maximum strength. In contrast, non-significant trends towards improvement (p &gt; 0.05) were observed in exercise capacity, reaction time, and muscular endurance. No significant changes (p > 0.05) were found in physiological and hormonal biomarkers and fatigue perception. However, perceived exertion was significantly higher (p &lt; 0.05) in SexG compared to AbsG. Conclusions: Current evidence does not conclusively support the influence of pre-exercise sexual activity on sports performance, or physiological and hormonal biomarkers. However, it could contribute to increased perception of exercise intensity.</dc:description>
<dc:date>2026-09-24T11:31:27Z</dc:date>
<dc:date>2026-09-24T11:31:27Z</dc:date>
<dc:date>2025-11</dc:date>
<dc:type>info:eu-repo/semantics/article</dc:type>
<dc:identifier>https://hdl.handle.net/10259/12142</dc:identifier>
<dc:identifier>10.3390/physiologia5040045</dc:identifier>
<dc:identifier>2673-9488</dc:identifier>
<dc:language>eng</dc:language>
<dc:relation>Physiologia. 2025, V. 5, n. 4, art 45</dc:relation>
<dc:relation>https://&#xd;
doi.org/10.3390/physiologia5040045</dc:relation>
<dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
<dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
<dc:rights>Atribución 4.0 Internacional</dc:rights>
<dc:publisher>MDPI</dc:publisher>
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