2026-10-09T03:10:53Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/122372026-10-08T00:05:28Zcom_10259_6168com_10259_5086com_10259_2604col_10259_12236

Fuente Vivas, Dalia de la 919 600 0000-0001-7037-1251 Casar, Berta 336f1f7c-a6e0-4903-8036-5ee3b2884cc3 600 Crespo, Piero ee8c65b4-46e5-478d-ad9a-9c30c2eb5730 600 2026-10-07T07:23:34Z 2026-10-07T07:23:34Z 2021 https://hdl.handle.net/10259/12237 Póster y resumen presentado en: 27th Porto Cancer Meeting "Stemness & Metastasis: Advances in Research and Clinical Translation" held online on 20-21 May 2021 Activation of the Ras-ERK signaling cascade is associated with increased metastasis risk inbreast cancer. In the present study. ERK dimerization plays a crucial role in the migrationand invasion of breast tumor cells. ERK dimers bind to the scaffold protein KSR1 toenhance migration. Blocking ERK dimers formation reduced invasion capacity of MCF-7and MDA-231-MB tumors cells. Thus, targeting ERK dimerization could emerge as a validtherapeutic strategy for the treatment of breast cancer. application/pdf eng Mamas-Cáncer Metástasis Breast-Cancer ERK dimerization promotes tumorigeneses in breast cancer ERK dimerization promotes migration in breast cancer info:eu-repo/semantics/conferenceObject info:eu-repo/semantics/acceptedVersion info:eu-repo/semantics/openAccess THUMBNAIL Fuente-Porto_Cancer_Meeting_2021.pdf.jpg Fuente-Porto_Cancer_Meeting_2021.pdf.jpg IM Thumbnail image/jpeg 6043 https://riubu.ubu.es/bitstream/10259/12237/4/Fuente-Porto_Cancer_Meeting_2021.pdf.jpg a6a637ff2dacee43e2fabefffa852788 MD5 4 Fuente-Porto_Cancer_Meeting_2021-Resumen.pdf.jpg Fuente-Porto_Cancer_Meeting_2021-Resumen.pdf.jpg IM Thumbnail image/jpeg 4098 https://riubu.ubu.es/bitstream/10259/12237/5/Fuente-Porto_Cancer_Meeting_2021-Resumen.pdf.jpg 4344e4f93fddea48ec74dcd7d341d1b3 MD5 5 LICENSE license.txt license.txt text/plain; charset=utf-8 1362 https://riubu.ubu.es/bitstream/10259/12237/2/license.txt 5d013bfa6e473ff0db22cd82a4d71a70 MD5 2 ORIGINAL Fuente-Porto_Cancer_Meeting_2021.pdf Fuente-Porto_Cancer_Meeting_2021.pdf Póster application/pdf 1002691 https://riubu.ubu.es/bitstream/10259/12237/1/Fuente-Porto_Cancer_Meeting_2021.pdf 9e5b9c009eef2a0c117fc0ee434fc571 MD5 1 Fuente-Porto_Cancer_Meeting_2021-Resumen.pdf Fuente-Porto_Cancer_Meeting_2021-Resumen.pdf Resumen application/pdf 158251 https://riubu.ubu.es/bitstream/10259/12237/3/Fuente-Porto_Cancer_Meeting_2021-Resumen.pdf 462c0727199bf1f7faf03eaa98dde855 MD5 3 10259/12237 oai:riubu.ubu.es:10259/12237 2026-10-08 02:05:28.331 Repositorio Institucional de la Universidad de Burgos bubrep@ubu.es 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