<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-07-02T04:21:49Z</responseDate><request verb="GetRecord" identifier="oai:riubu.ubu.es:10259/3533" metadataPrefix="dim">https://riubu.ubu.es/oai/request</request><GetRecord><record><header><identifier>oai:riubu.ubu.es:10259/3533</identifier><datestamp>2024-07-18T09:38:39Z</datestamp><setSpec>com_10259_9433</setSpec><setSpec>com_10259_5087</setSpec><setSpec>com_10259_2728</setSpec><setSpec>col_10259_9434</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:doc="http://www.lyncode.com/xoai" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
<dim:field mdschema="dc" element="contributor" qualifier="advisor" authority="159" confidence="500" orcid_id="0000-0003-2067-0274">Domínguez Renedo, Olga</dim:field>
<dim:field mdschema="dc" element="contributor" qualifier="author" authority="d97dedeb-7214-4fe1-b0f9-6df0d948640c" confidence="500" orcid_id="">Sancho Querol, Sara</dim:field>
<dim:field mdschema="dc" element="contributor" qualifier="other" authority="cdb9be44-6a4e-4c59-a087-29b53a5cbbc9" confidence="500" orcid_id="">Universidad de Burgos. Departamento de Química</dim:field>
<dim:field mdschema="dc" element="date" qualifier="accessioned">2014-10-21T10:06:26Z</dim:field>
<dim:field mdschema="dc" element="date" qualifier="available">2014-10-21T10:06:26Z</dim:field>
<dim:field mdschema="dc" element="date" qualifier="submitted">2014</dim:field>
<dim:field mdschema="dc" element="identifier" qualifier="uri">http://hdl.handle.net/10259/3533</dim:field>
<dim:field mdschema="dc" element="description" qualifier="abstract" lang="en">This work reports the development of two different sensors using screen-printed carbon electrodes (SPCEs) for the determination of imipramine (IMP) by differential pulse voltammetry. On one hand, a bare SPCE has been successfully applied to the determination of this compound and, on the other hand, the modification of this SPCE with metallic gold nanoparticles (AuNPs/SPCE) have led to an increase in the sensitivity of IMP determination. Both sensors have been characterized obtaining good capability of detection (14.1 μM and 0.28 μM for SPCE and AuNPs/SPCE, respectively) and reproducibility (4.75 % and 6.87 % for SPCE and AuNPs/SPCE, respectively) values. The specificity of both sensors towards different compounds has been also analyzed and, the developed electrochemical systems have been successfully applied in the determination of IMP in commercial pharmaceutical preparations.</dim:field>
<dim:field mdschema="dc" element="format" qualifier="mimetype">application/pdf</dim:field>
<dim:field mdschema="dc" element="language" qualifier="iso" lang="es">spa</dim:field>
<dim:field mdschema="dc" element="rights">Attribution-NonCommercial-NoDerivatives 4.0 International</dim:field>
<dim:field mdschema="dc" element="rights" qualifier="uri">http://creativecommons.org/licenses/by-nc-nd/4.0/</dim:field>
<dim:field mdschema="dc" element="rights" qualifier="holder">Este documento está sujeto a una licencia de uso Creative Commons, por la cual está permitido hacer copia, distribuir y comunicar públicamente la obra siempre que se cite al autor original y no se haga de él uso comercial ni obra derivada</dim:field>
<dim:field mdschema="dc" element="rights" qualifier="accessRights">info:eu-repo/semantics/openAccess</dim:field>
<dim:field mdschema="dc" element="subject" qualifier="other" lang="es">Química analítica</dim:field>
<dim:field mdschema="dc" element="subject" qualifier="other" lang="en">Chemistry, Analytic</dim:field>
<dim:field mdschema="dc" element="title">Puesta a punto de un biosensor para la determinación de analitos de interés en el tratamiento de trastornos depresivos: detección electroquímica de imipramina</dim:field>
<dim:field mdschema="dc" element="type">info:eu-repo/semantics/bachelorThesis</dim:field>
<dim:field mdschema="dc" element="type" qualifier="hasVersion">info:eu-repo/semantics/acceptedVersion</dim:field>
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