2026-07-02T07:21:51Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/35332024-07-18T09:38:39Zcom_10259_9433com_10259_5087com_10259_2728col_10259_9434

Domínguez Renedo, Olga Universidad de Burgos. Departamento de Química Sancho Querol, Sara This work reports the development of two different sensors using screen-printed carbon electrodes (SPCEs) for the determination of imipramine (IMP) by differential pulse voltammetry. On one hand, a bare SPCE has been successfully applied to the determination of this compound and, on the other hand, the modification of this SPCE with metallic gold nanoparticles (AuNPs/SPCE) have led to an increase in the sensitivity of IMP determination. Both sensors have been characterized obtaining good capability of detection (14.1 μM and 0.28 μM for SPCE and AuNPs/SPCE, respectively) and reproducibility (4.75 % and 6.87 % for SPCE and AuNPs/SPCE, respectively) values. The specificity of both sensors towards different compounds has been also analyzed and, the developed electrochemical systems have been successfully applied in the determination of IMP in commercial pharmaceutical preparations. application/pdf http://hdl.handle.net/10259/3533 spa Puesta a punto de un biosensor para la determinación de analitos de interés en el tratamiento de trastornos depresivos: detección electroquímica de imipramina info:eu-repo/semantics/bachelorThesis TEXT RIUBU. Repositorio Institucional de la Universidad de Burgos Hispana