2026-05-30T19:26:49Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/39092021-11-10T09:38:19Zcom_10259_3593com_10259_5086com_10259_2604com_10259_3924col_10259_3594col_10259_3925

00925njm 22002777a 4500 dc Guilarte Moreno, Verónica author Fernández Rodríguez, Manuel A. author García García, Patricia author Hernando Santa Cruz, Elsa author Sanz Díez, Roberto author 2011-09 An efficient synthesis of thiophenes and benzo[b]thiophenes has been developed from easily available bromoenynes and o-alkynylbromobenzene derivatives. This novel one-pot procedure involves a Pd-catalyzed C–S bond formation using a hydrogen sulfide surrogate followed by a heterocyclization reaction. Moreover, in situ functionalization with selected electrophiles further expands the potential of this methodology to the preparation of the corresponding highly substituted sulfur heterocycles. 1523-7060 http://hdl.handle.net/10259/3909 10.1021/ol201970m A Practical, One-Pot Synthesis of Highly Substituted Thiophenes and Benzo[b]thiophenes from Bromoenynes and o-Alkynylbromobenzenes