2026-06-19T16:33:20Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/42782022-04-29T12:02:48Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594

00925njm 22002777a 4500 dc Álvarez Manuel, Estela author Nieto Faza, Olalla . author Silva López, Carlos author Fernández Rodríguez, Manuel A. author Sanz Díez, Roberto author 2015-09 A cascade reaction of indoles with propargylic diols involving an unprecedented metal-free 1,2-indole migration onto an alkyne is here described. DFT calculations support a mechanism consisting in a concerted nucleophilic attack of the indole nucleus with loss of water followed by the 1,2-migration and subsequent Nazarov cyclization. This Brønsted acid-catalyzed protocol affords indole-functionalized benzofulvene derivatives in high yields. 0947-6539 http://hdl.handle.net/10259/4278 benzofulvenes Brønsted acid catalysis indolemigration Nazarov cyclization Brønsted Acid-Catalyzed Cascade Reactions Involving 1,2-Indole Migration