2026-08-23T18:24:24Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/43592022-04-29T12:02:48Zcom_10259_4313com_10259_5086com_10259_2604com_10259_4365col_10259_4314col_10259_4366
Repositorio Institucional de la Universidad de Burgos
author
Vallejos Calzada, Saúl
author
Estévez Bolívar, Pedro Antonio
author
Ibeas Cortes, Saturnino
author
García García, Félix Clemente
author
Serna Arenas, Felipe
author
García Pérez, José Miguel
2017-03-14T09:48:16Z
2017-03-14T09:48:16Z
2012-03
1424-8220
http://hdl.handle.net/10259/4359
10.3390/s120302969
The preparation of a fluorogenic sensory material for the detection of biomolecules is described. Strategic functionalisation and copolymerisation of a water insoluble organic sensory molecule with hydrophilic comonomers yielded a crosslinked, water-swellable, easy-to-manipulate solid system for water ‘‘dip-in’’ fluorogenic coenzyme A, cysteine, and glutathione detection by means of host-guest interactions. The sensory material was a membrane with gel-like behaviour, which exhibits a change in fluorescence behaviour upon swelling with a water solution of the target molecules. The membrane follows a “turn-on” pattern, which permits the titration of the abovementioned biomolecules. In this way, the water insoluble sensing motif can be exploited in aqueous media. The sensory motif within the membrane is a chemically anchored piperazinedione-derivative with a weakly bound Hg(II). The response is caused by the displacement of the cation from the membrane due to a stronger complexation with the biomolecules, thus releasing the fluorescent sensory moieties within the membrane
eng
Attribution 3.0 Unported
sensory materials
chemosensor
fluorogenic sensor
biomolecules
sensing biomolecules
An Organic/Inorganic Hybrid Membrane as a Solid “Turn-On” Fluorescent Chemosensor for Coenzyme A (CoA), Cysteine (Cys), and Glutathione (GSH) in Aqueous Media
info:eu-repo/semantics/article
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URL
https://riubu.ubu.es/bitstream/10259/4359/1/Vallejos-Sensors_2012.pdf
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Vallejos-Sensors_2012.pdf
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https://riubu.ubu.es/bitstream/10259/4359/6/Vallejos-Sensors_2012.pdf.txt
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Vallejos-Sensors_2012.pdf.txt