2026-06-21T22:31:10Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/43922022-05-20T13:22:32Zcom_10259_4862com_10259_5086com_10259_2604col_10259_4863

00925njm 22002777a 4500 dc Fernández Natal, Isabel author Sáez Nieto, J. A. author Rodríguez Lázaro, David author Valdezate Ramos, S. author Parras Padilla, T. author Medina, M. J. author Rodríguez Pollán, R. H. author Blom, J. author Tauch, A. author Soriano, F. author 2016-03 During a 12-year period we isolated five Corynebacterium argentoratense strains identified by phenotypic methods, including the use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) and 16S rRNA gene sequencing. In addition, antimicrobial susceptibility was determined, and genome sequencing for the detection of antibiotic resistance genes was performed. The organisms were isolated from blood and throat cultures and could be identified by all methods used. All strains were resistant to cotrimoxazole, and resistance to β-lactams was partly present. Two strains were resistant to erythromycin and clindamycin. The draft genome sequences of theses isolates revealed the presence of the erm(X) resistance gene that is embedded in the genetic structure of the transposable element Tn5423. Although rarely reported as a human pathogen, C. argentoratense can be involved in bacteraemia and probably in other infections. Our results also show that horizontal transfer of genes responsible for antibiotic resistance is occurring in this species. http://hdl.handle.net/10259/4392 Antimicrobial resistance clinical infections Corynebacterium argentoratense MALDI-TOF whole genome sequencing Phenotypic, molecular characterization, antimicrobial susceptibility and draft genome sequence of Corynebacterium argentoratense strains isolated from clinical samples