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oai:riubu.ubu.es:10259/45292022-05-20T13:22:37Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594

Suárez, Anisley Martínez Lara, Fernando Suarez Pantiga, Samuel Sanz Díez, Roberto 2017-07-13T10:26:42Z 2018-01-13T03:45:06Z 2017-01 2365-6549 http://hdl.handle.net/10259/4529 10.1002/slct.201700013 A convenient procedure for accessing a,a-bis(indol-3-yl) ketones from indoles and a-oxoaldehydes is described using an inexpensive and commercially available catalyst such as ptoluenesulfonic acid monohydrate. This protocol allows for the first time the synthesis of 2,2-bis(indolyl)-1-alkylethanones by employing aliphatic 2-oxoaldehydes, even as aqueous solutions. The high-yielded obtained ketones have been shown as useful starting materials for further synthetic transformations. Ministerio de Economía y Competitividad (MINECO) and FEDER (CTQ2013-48937-C2-1P) and Junta de Castilla y León and FEDER (BU076U16) This is the peer reviewed version of the following article: A. Suárez, F. Martínez, S. Suárez-Pantiga, R. Sanz, ChemistrySelect 2017, 2, 787. doi: 10.1002/slct.201700013, which has been published in final form at 10.1002/slct.201700013. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving application/pdf eng Wiley-VCH Verlag Chemistry Select. 2017, V. 2, n. 2, p. 787–790 http://dx.doi.org/10.1002/slct.201700013 Química orgánica Chemistry, Organic PTSA-Catalyzed Reaction of Indoles with 2-Oxoaldehydes: Synthesis of α,α-Bis(indol-3-yl) Ketones info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion info:eu-repo/semantics/openAccess