2026-06-17T21:28:32Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/45292022-05-20T13:22:37Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594

PTSA-Catalyzed Reaction of Indoles with 2-Oxoaldehydes: Synthesis of α,α-Bis(indol-3-yl) Ketones Suárez, Anisley Martínez Lara, Fernando Suarez Pantiga, Samuel Sanz Díez, Roberto A convenient procedure for accessing a,a-bis(indol-3-yl) ketones from indoles and a-oxoaldehydes is described using an inexpensive and commercially available catalyst such as ptoluenesulfonic acid monohydrate. This protocol allows for the first time the synthesis of 2,2-bis(indolyl)-1-alkylethanones by employing aliphatic 2-oxoaldehydes, even as aqueous solutions. The high-yielded obtained ketones have been shown as useful starting materials for further synthetic transformations. 2017-07-13T10:26:42Z 2018-01-13T03:45:06Z 2017-01 info:eu-repo/semantics/article 2365-6549 http://hdl.handle.net/10259/4529 10.1002/slct.201700013 eng Chemistry Select. 2017, V. 2, n. 2, p. 787–790 http://dx.doi.org/10.1002/slct.201700013 info:eu-repo/semantics/openAccess Wiley-VCH Verlag