2026-07-11T09:50:31Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/50772021-11-10T09:38:20Zcom_10259_4244com_10259_5086com_10259_2604col_10259_4245

Melgosa Gómez, Rodrigo Sanz Díez, Mª Teresa Benito Román, Oscar Illera Gigante, Alba Ester Beltrán Calvo, Sagrario 2019-03-20T09:00:14Z 2019-05 2021-06 2212-9820 http://hdl.handle.net/10259/5077 10.1016/j.jcou.2019.02.015 Supercritical carbon dioxide (SC−CO2) has been used as solvent in the ethanolysis of fish oil rich with omega-3 polyunsaturated fatty acids (n-3 PUFAs) by Lipozyme 435. The effect of experimental conditions: initial ethanol-to-oil molar ratio (MR, 6:1-76:1), pressure (10–30 MPa), and temperature (323–343 K) on the reaction performance has been studied. Experimental results have been fitted to a kinetic model based on a Ping Pong Bi Bi mechanism. High accumulation of monoacylglycerides (MAGs) has been observed in short reaction times (90 min at MR = 76:1, 10 MPa, 323 K). Subsequent purification of reaction products by supercritical fluid extraction (SFE) in the experimental range 10–28 MPa and 298–333 K yielded an extract rich with fatty acid ethyl esters (FAEE) (up to 99.46%wt.), and a raffinate with up to 82.25%wt. MAG and 49.5%wt. n-3 PUFAs. Spanish Government through MINECO and the European Regional Development Fund (ERDF) for financial support [grant number CTQ2012-39131-C02-01] and RM’s and AEI’s contracts [BES-2013-063937, CTQ2015-64396-R]. To Junta de Castilla y León and ERDF for financial support [grant number BU055U16] and ÓBR’s post-doctoral contract. application/pdf eng Elsevier Journal of CO2 Utilization. 2019, V. 31, p. 65-74 https://doi.org/10.1016/j.jcou.2019.02.015 info:eu-repo/grantAgreement/MINECO/CTQ2012-39131-C02-01 info:eu-repo/grantAgreement/JCyL/BU055U16 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Omega 3 Lipase Ethanolysis Supercritical carbon dioxide Supercritical fluid extraction Ingeniería química Chemical engineering Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion