2026-07-11T08:17:14Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/50772021-11-10T09:38:20Zcom_10259_4244com_10259_5086com_10259_2604col_10259_4245

00925njm 22002777a 4500 dc Melgosa Gómez, Rodrigo author Sanz Díez, Mª Teresa author Benito Román, Oscar author Illera Gigante, Alba Ester author Beltrán Calvo, Sagrario author 2019-05 Supercritical carbon dioxide (SC−CO2) has been used as solvent in the ethanolysis of fish oil rich with omega-3 polyunsaturated fatty acids (n-3 PUFAs) by Lipozyme 435. The effect of experimental conditions: initial ethanol-to-oil molar ratio (MR, 6:1-76:1), pressure (10–30 MPa), and temperature (323–343 K) on the reaction performance has been studied. Experimental results have been fitted to a kinetic model based on a Ping Pong Bi Bi mechanism. High accumulation of monoacylglycerides (MAGs) has been observed in short reaction times (90 min at MR = 76:1, 10 MPa, 323 K). Subsequent purification of reaction products by supercritical fluid extraction (SFE) in the experimental range 10–28 MPa and 298–333 K yielded an extract rich with fatty acid ethyl esters (FAEE) (up to 99.46%wt.), and a raffinate with up to 82.25%wt. MAG and 49.5%wt. n-3 PUFAs. 2212-9820 http://hdl.handle.net/10259/5077 10.1016/j.jcou.2019.02.015 Omega 3 Lipase Ethanolysis Supercritical carbon dioxide Supercritical fluid extraction Supercritical CO2 assisted synthesis and concentration of monoacylglycerides rich in omega-3 polyunsaturated fatty acids