2026-06-17T20:15:59Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/53452022-04-08T10:18:38Zcom_10259_4376com_10259_5086com_10259_2604col_10259_4377

Molinero Abad, Begoña Pérez Ruiz, Lydia Izquierdo Bote, Daniel Escudero Barbero, Isabel Arcos Martínez, Julia 2020-06-17T13:27:02Z 2020-06-17T13:27:02Z 2019-01 0039-9140 http://hdl.handle.net/10259/5345 10.1016/j.talanta.2018.09.072 The monitoring of marine dinophysistoxin okadaic acid in seawater can serve as an early alert system for preventing the potential negative effects this toxin can have on the food industry and human health in general. A disposable sensor system for electrochemical detection of this toxin has been developed using screen-printed electrodes. The method described is based on the inhibition of protein phosphatase type 2A by okadaic acid, evaluating the enzyme activity. p-Nitrophenyl phosphate, 4-methylumbelliferyl phosphate and phenyl phosphate have been tested as substrates achieving good limits of detection of 2.7·10–12 M of okadaic acid. The proposed method has been successfully applied to okadaic acid determination in seawater samples. A study of divalent cations present in seawater that can interfere with the measurement has been carried out. The electrode systems were printed on both rigid and textile backing materials to observe the influence of those materials on the final performance of the sensor. Ministerio de Ciencia e Innovación (MICINN) (TEC2013-405661-P) Ministerio de Economía y Competitividad (MINECO) and European Regional Development Fund (FEDER) (MUSSEL RTC-2015-4077-2). application/pdf eng Elsevier Talanta. 2019, V. 192, p. 347-352 https://doi.org/10.1016/j.talanta.2018.09.072 info:eu-repo/grantAgreement/MICINN/TEC2013-405661-P info:eu-repo/grantAgreement/MINECO/MUSSEL RTC-2015-4077-2) Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Okadaic acid Screen printed electrodes Textile sensors Seawater PP2A Química analítica Chemistry, Analytic Sensor system based on flexible screen-printed electrodes for electrochemical detection of okadaic acid in seawater info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Talanta 192 347 352