2026-10-12T14:53:33Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/53652021-11-02T12:02:54Zcom_10259_5363com_10259_5086com_10259_2604col_10259_5364
Repositorio Institucional de la Universidad de Burgos
author
Gargouri, Wafa
author
Osés Gómez, Sandra María
author
Fernández Muiño, Miguel Ángel
author
Sancho Ortiz, María Teresa
author
Kechaou, Nabil
2020-07-02T09:35:44Z
2020-07-02T09:35:44Z
2019-08
0023-6438
http://hdl.handle.net/10259/5365
10.1016/j.lwt.2019.05.044
The aim of this study was to investigate the phytochemical composition and biological properties of Tunisian propolis from four different regions: Kasserine, Béja, Kèf and Monastir. Ethanolic extracts of propolis were prepared using two extraction methods; solvent and ultrasonic extraction. Total phenolics, flavonoids, ABTS free radical and hydroxyl radicals scavenging abilities, anti-inflammatory, anti-hypertensive, as well as antimicrobial activities of propolis extracts were determined. Identification and quantification of phenolic and flavonoid compounds were performed by using both HPLC-UV and HPLC-ESI-MS. The results revealed high contents of total phenolics and flavonoids and polyphenols extraction was more efficient by sonication. Caffeic acid phenethyl ester (CAPE), galangin, and genistein were the major identified compounds. Antihypertensive activity, evaluated in propolis extracts for first time by HPLC-UV, was higher than 90% for all extracts. Tunisian propolis is an important natural source of polyphenols and flavonoids. The best extraction method was ultrasonic for antioxidants and most of biological activities; conventional method seems to be more suitable for anti-inflammatory activity. Propolis from Béja contains the highest amount of antioxidants and have a stronger potential biological activities. Tunisian propolis could be, therefore, a promising raw material for food and pharmaceutical industry.
eng
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Propolis
Phenolics
HPLC-UV
Antioxidant activity
ACE
Evaluation of bioactive compounds and biological activities of Tunisian propolis
info:eu-repo/semantics/article
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URL
https://riubu.ubu.es/bitstream/10259/5365/1/Gargouri-lwt_2019.pdf
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https://riubu.ubu.es/bitstream/10259/5365/5/Gargouri-lwt_2019.pdf.txt
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