2026-07-11T15:51:54Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/55972022-09-14T22:42:06Zcom_10259_4376com_10259_5086com_10259_2604col_10259_4377

00925njm 22002777a 4500 dc Ott, Colby E. author Cunha Silva, Hugo author Kuberski, Sara L author Cox, Joseph A. author Arcos Martínez, Julia author Arroyo Mora, Luís E. author 2020-09 Square-wave adsorptive stripping voltammetry (SWAdSV) is proposed as a fast, simple, and sensitive approach toward the detection, identification, and semi-quantitation of fentanyl in seized drug samples using screen-printed carbon electrodes. Electrochemical oxidation of fentanyl resulted in the formation of two anodic peaks, one at 0.75 V (peak I) and the second at 0.88 V (peak II) versus a Ag/AgCl pseudo reference electrode. Voltammetric measurements were conducted under optimized experimental conditions using fentanyl standards ranging from 0.076 μg/mL to 6.9 μg/mL, which resulted in a limit of detection of 0.037 μg/mL. Reproducibility was assessed as the average percent relative standard deviation of the slopes of calibration curves and was 2.6% for oxidation peak I and 7.4% for oxidation peak II in cell. Detection capabilities were assessed in a 5-mL cell and in a 100 microliter drop. Interference studies were conducted with cocaine, methamphetamine, quinine, caffeine, and acetaminophen. The mechanism for the electrochemical oxidation of fentanyl to norfentanyl is also described. Accuracy and suitability of the method for seized drug analysis was assessed using 11 simulated samples. Suitability of the method for future analysis of fentanyl in oral fluid was assessed. 1572-6657 http://hdl.handle.net/10259/5597 10.1016/j.jelechem.2020.114425 Fentanyl Screen-printed electrodesFentanyl voltammetric determination Forensic science Oral fluid Seized drugs Electrochemical detection of fentanyl with screen-printed carbon electrodes using square-wave adsorptive stripping voltammetry for forensic applications