2026-09-09T11:29:33Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/61182025-02-14T12:56:29Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845

Olmo Alonso, Fabiola Rodríguez Rubio, Andrea Colina Santamaría, Álvaro Heras Vidaurre, Aránzazu 2021-11-08T12:01:45Z 2021-11-08T12:01:45Z 2021-08 1433-0768 http://hdl.handle.net/10259/6118 10.1007/s10008-021-05026-5 UV/Vis absorption spectroelectrochemistry is a very promising analytical technique due to the complementary information that is simultaneously obtained from electrochemistry and spectroscopy. In this work, this technique is used in a parallel configuration to study the oxidation of folic acid in alkaline medium. Herein, UV/Vis absorption spectroelectrochemistry has been used to detect both the oxidation products and the folic acid consumed at the electrode/solution interface, allowing us to develop an analytical protocol to quantify vitamin B9 in pharmaceutical tablets. Linear ranges of three orders of magnitude have been achieved in basic medium (pH = 12.9), obtaining high repeatability and low detection limits. The spectroelectrochemical determination of folic acid in pharmaceutical tablets at alkaline pH values is particularly interesting because of the changes that occur in the optical signal during the electrochemical oxidation of FA, providing results with very good figures of merit and demonstrating the utility and versatility of this hyphenated technique, UV/Vis absorption spectroelectrochemistry. eng http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Atribución 4.0 Internacional Vitamin B9 Pharmaceutical drug Electrochemistry UV/Vis absorption spectroscopy UV/Vis absorption spectroelectrochemistry of folic acid info:eu-repo/semantics/article