2026-09-13T17:17:16Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/61212022-11-11T13:56:43Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845

00925njm 22002777a 4500 dc Olmo Alonso, Fabiola author Garoz Ruiz, Jesús author Carazo, Julia author Colina Santamaría, Álvaro author Heras Vidaurre, Aránzazu author 2020-09 UV/Vis absorption spectroelectrochemistry (SEC) is a multi-response technique that has been commonly used for the characterization of materials and the study of reaction mechanisms. However, it has been scarcely used for quantitative purposes. SEC allows us to obtain two analytical signals simultaneously, yielding a dual sensor in just one experiment. In the last years, our group has developed new devices useful for analysis. In this work, a SEC device in parallel configuration, based on optical fibers fixed on screen-printed electrodes, was used to determine isoprenaline in a commercial drug, using both, the electrochemical and the spectroscopic signals. In this commercial drug, isoprenaline is accompanied in solution by other compounds. Among them is sodium metabisulfite, an antioxidant that strongly interferes in the isoprenaline determination. A simple pretreatment of the drug sample by bubbling wet-air allows us to avoid the interference of metabisulfite. Here, we demonstrate again the capabilities of UV/Vis absorption SEC as double sensor for analysis and we propose a simple pretreatment to remove interfering compounds. 1424-8220 http://hdl.handle.net/10259/6121 10.3390/s20185179 Spectroelectrochemistry Electrochemistry UV/Vis absorption Drug analysis Isoproterenol Metabisulfite Spectroelectrochemical Determination of Isoprenaline in a Pharmaceutical Sample