2026-06-17T21:40:37Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/61282025-07-28T08:13:46Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845

Cheuquepan Valenzuela, William Hernández Muñoz, Sheila Pérez Estébanez, Martín Romay García, Luis Heras Vidaurre, Aránzazu Colina Santamaría, Álvaro 2021-11-09T09:53:16Z 2021-11-09T09:53:16Z 2021-09 1572-6657 http://hdl.handle.net/10259/6128 10.1016/j.jelechem.2021.115288 Electrochemistry is a very useful technique to generate surface enhanced Raman scattering (SERS) substrates. SERS depends on two mechanisms: the electromagnetic effect, related to the plasmonic properties of the nanostructures in the substrate, and the chemical mechanism, related to the interaction between the target molecule and the substrate. Thus, Raman enhancement for a molecule strongly depends on the nature of the nanostructures that form the substrate. In this work, time-resolved Raman spectroelectrochemistry is used to generate SERS substrates, obtaining the Raman signal during the generation of the substrate, which is very useful to obtain valuable information on the Raman performance of the substrate. Two metals, Au and Ag, have been used to determine folic acid in a drug. In this example, Au SERS substrates are highly influenced by interfering compounds present in the drug tables. On the contrary, Ag SERS substrates have been demonstrated to yield very good figures of merit in the determination of folic acid in this complex sample. Ministerio de Economía, y Competitividad (Grant CTQ2017-83935-R-AEI/FEDERUE), Junta de Castilla y León (Grant BU297P18) and Ministerio de Ciencia, Innovación y Universidades (Grant RED2018-102412-T). W. Ch. thanks JCyL for his postdoctoral fellowship (Grant BU297P18). application/pdf spa Elsevier Journal of Electroanalytical Chemistry. 2021, V. 896, 115288 https://doi.org/10.1016/j.jelechem.2021.115288 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2017-83935-R/ES/ESPECTROELECTROQUIMICA RAMAN CUANTITATIVA info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/ RED2018-102412-T/ES/RED DE SENSORES Y BIOSENSORES ELECTROQUIMICOS info:eu-repo/grantAgreement/Junta de Castilla y León//BU297P18 Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess Spectroelectrochemistry Surface enhanced Raman Scattering SERS RAMAN Química analítica Chemistry, Analytic Electrochemical generation of surface enhanced Raman scattering substrates for the determination of folic acid info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion