2026-05-30T12:49:54Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/61302022-12-14T23:42:07Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845

Hernández Muñoz, Sheila Perales Rondon, Juan Víctor Arnaiz, Alvaro Pérez Estébanez, Martín Gomez, Elvira Colina Santamaría, Álvaro Heras Vidaurre, Aránzazu 2021-11-09T10:39:47Z 2021-11-09T10:39:47Z 2020-12 1572-6657 http://hdl.handle.net/10259/6130 10.1016/j.jelechem.2020.114743 Time resolved Raman spectroelectrochemistry is a powerful technique to prepare useful Surface Enhanced Raman Scattering (SERS) substrates suitable for quantitative analysis. Moreover, following the evolution of the Raman signal with the applied potential the selection of the best conditions for the analysis is quite simple. In this work, gold SERS substrates are prepared on screen-printed electrodes for the determination of nicotinamide, vitamin B3, in a multivitamin complex. The formation of the substrate has been monitored using UV/Vis absorption spectroelectrochemistry and scanning electron microscopy, which confirmed the generation of gold nanoparticles on the electrode surface. This new method has demonstrated to be suitable for the direct quantification of simple test samples using small sample volumes (50 μL). However, it failed when a complex sample, containing several interfering species, was analysed. A high interference on the preparation of the SERS substrate is observed during the analysis of a multivitamin complex. Despite that, nicotinamide was selectively determined in a multivitamin complex using the method of the standard addition, obtaining remarkable figures of merit (R2 = 0.99, %RSD < 9%). Ministerio de Economía, y Competitividad (Grant CTQ2017-83935-R-AEI/FEDERUE), Junta de Castilla y León (Grant BU297P18) and Ministerio de Ciencia, Innovación y Universidades (Grant RED2018-102412-T). J.V.P-R. thanks Junta de Castilla y León for his postdoctoral fellowship (Grant BU033-U16) application/pdf spa Elsevier Journal of Electroanalytical Chemistry. 2020, V. 879, 114743 https://doi.org/10.1016/j.jelechem.2020.114743 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2017-83935-R/ES/ESPECTROELECTROQUIMICA RAMAN CUANTITATIVA info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/ RED2018-102412-T/ES/RED DE SENSORES Y BIOSENSORES ELECTROQUIMICOS info:eu-repo/grantAgreement/Junta de Castilla y León//BU033-U16//Desarrollo de un equipo compacto de espectroelectroquímica Raman info:eu-repo/grantAgreement/Junta de Castilla y León//BU297P18 Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Spectroelectrochemistry Vitamin B3 EC-SERS Raman spectroscopy Standard addition method Química analítica Chemistry, Analytic Determination of nicotinamide in a multivitamin complex by electrochemical-surface enhanced Raman spectroscopy info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion