2026-06-17T18:11:47Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/74132023-03-27T12:27:39Zcom_10259_3592com_10259_3591com_10259.4_106com_10259_2604com_10259_3593com_10259_5086col_10259_3930col_10259_3594

Velasco Pérez, Noelia Martínez Núñez, Clara Fernández Rodríguez, Manuel A. Sanz Díez, Roberto Suarez Pantiga, Samuel 2023-02-07T12:10:37Z 2023-02-07T12:10:37Z 2022-07 1615-4150 http://hdl.handle.net/10259/7413 10.1002/adsc.202200613 1615-4169 A tandem 1,3-sulfur migration followed by iodocyclization reaction of propargylic sulfides in the presence of NIS in HFIP has been developed to synthesize indene-based β-iodoalkenyl sulfides. The choice of the reaction media is crucial to promote the reaction. The proposed mechanism involving the initial NIS activation by HFIP and favoring the sulfur migration of the starting propargylic thioether via cationic intermediates is experimentally supported. In addition, the suitability of selected indene-based β-iodoalkenyl sulfides as building blocks for subsequent C C bond-forming reactions has been demonstrated. eng http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess Atribución-NoComercial 4.0 Internacional Synthetic methods Sulfur Alkenes Alkynes Halogens NIS/HFIP‐Mediated Synthesis of Indene‐Based β‐Iodoalkenyl Sulfides from Propargylic Sulfides info:eu-repo/semantics/article