2026-06-21T19:20:49Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/75742023-04-19T09:31:07Zcom_10259_4141com_10259_5086com_10259_2604com_10259_4415com_10259_3989com_10259.4_106com_10259_7575com_10259_7328col_10259_4142col_10259_4416col_10259_7576col_10259_7329

Accelerometer Cut-Points for Physical Activity Assessment in Adults with Mild to Moderate Huntington’s Disease: A Cross-Sectional Multicentre Study Simón Vicente, Lucía Rivadeneyra Posadas, Jéssica Jannett Soto Célix, María . Raya-González, Javier Castillo, Daniel Calvo Simal, Sara Collazo Riobó, Carla Rodríguez Fernández, Alejandro Fahed, Vitoria S. Mariscal, Natividad García Bustillo, Álvaro Aguado, Laura Cubo Delgado, Esther Accelerometry Energy metabolism Rehabilitation Actigraphy Calorimetry Indirect Salud Medicina Health Medicine Accelerometers can estimate the intensity, frequency, and duration of physical activity in healthy adults. Although thresholds to distinguish varying levels of activity intensity using the Actigraph wGT3X-B have been established for the general population, their accuracy for Huntington’s disease (HD) is unknown. We aimed to define and cross-validate accelerometer cut-points for different walking speeds in adults with mild to moderate HD. A cross-sectional, multicentre, case-control, observational study was conducted with a convenience sample of 13 symptomatic ambulatory HD participants. The accelerometer was placed around the right hip, and a heart monitor was fitted around the chest to monitor heart rate variability. Participants walked on a treadmill at three speeds with light, moderate and vigorous intensities. Correlation and receiver operation curve analyses were performed between the accelerometer magnitude vector with relative oxygen and heart rate. Optimal cut-points for walking speeds of 3.2 km/h were ≤2852; 5.2 km/h: >2852 to ≤4117, and in increments until their maximum velocity: >4117. Our results support the application of the disease-specific cut-points for quantifying physical activity in patients with mild to moderate HD and promoting healthy lifestyle interventions. The project leading to these results has received funding from “La Caixa” Foundation (ID100010434), under agreement FUI1-PI008. 2023-03-21T12:01:09Z 2023-03-21T12:01:09Z 2022-11 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/10259/7574 10.3390/ijerph192214834 1660-4601 eng International Journal of Environmental Research and Public Health. 2022, V. 19, n. 22, 14834 https://doi.org/10.3390/ijerph192214834 info:eu-repo/grantAgreement/Fundación Bancaria Caixa d'Estalvis i Pensions de Barcelona//FUI1-PI008/ Atribución 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess application/pdf MDPI https://riubu.ubu.es/bitstream/10259/7574/4/Simon-ijerph_2022.pdf.jpg Hispana TEXT http://creativecommons.org/licenses/by/4.0/ RIUBU. Repositorio Institucional de la Universidad de Burgos http://hdl.handle.net/10259/7574