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<dc:title>Effects of Tribulus terrestris L. on Sport and Health Biomarkers in Physically Active Adult Males: A Systematic Review</dc:title>
<dc:creator>Fernández-Lázaro, Diego</dc:creator>
<dc:creator>Fernández-Lázaro, César I.</dc:creator>
<dc:creator>Seco-Calvo, Jesús</dc:creator>
<dc:creator>Garrosa, Evalina</dc:creator>
<dc:creator>Adams, David P.</dc:creator>
<dc:creator>Mielgo Ayuso, Juan</dc:creator>
<dc:subject>Tribulus terrestris</dc:subject>
<dc:subject>Sport supplement</dc:subject>
<dc:subject>Biomarkers</dc:subject>
<dc:subject>Physically active adults</dc:subject>
<dc:subject>Systematic review</dc:subject>
<dc:subject>Fisiología</dc:subject>
<dc:subject>Deportes</dc:subject>
<dc:subject>Physiology</dc:subject>
<dc:subject>Sports</dc:subject>
<dc:description>Tribulus terrestris L. (TT) is a plant used in traditional Chinese medicine, Ayurvedic medicine,&#xd;
and sports nutrition to improve health and performance. However, no conclusive evidence exists&#xd;
about the potential beneficial effects of TT on sport and health biomarkers in physically active&#xd;
adults. Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)&#xd;
guidelines, and the modified McMaster Critical Review Form for methodological quality assessment,&#xd;
we systematically reviewed studies indexed in Web of Science, Scopus, and PubMed, to assess&#xd;
the effects of TT on immunological, hematological, biochemical, renal, lipidic, hormonal behavior,&#xd;
and anti-inflammatory response in physically active adult males. Among 340 records identified&#xd;
in the search, a total of 7 studies met the inclusion and exclusion criteria. Overall, participants&#xd;
supplemented with TT displayed significant improvements in lipid profile. Inflammatory and&#xd;
hematological biomarkers showed moderate beneficial effects with no significant changes on renal&#xd;
biomarkers. No positive effects were observed on the immune system response. Additionally, no&#xd;
TT-induced toxicity was reported. In conclusion, there was no clear evidence of the beneficial effects&#xd;
of TT supplementation on muscle damage markers and hormonal behavior. More studies are needed&#xd;
to confirm the benefits of TT due to the limited number of studies available in the current literature.</dc:description>
<dc:date>2023-03-24T08:00:14Z</dc:date>
<dc:date>2023-03-24T08:00:14Z</dc:date>
<dc:date>2022-08</dc:date>
<dc:type>info:eu-repo/semantics/article</dc:type>
<dc:type>info:eu-repo/semantics/publishedVersion</dc:type>
<dc:identifier>http://hdl.handle.net/10259/7593</dc:identifier>
<dc:identifier>10.3390/ijerph19159533</dc:identifier>
<dc:identifier>1660-4601</dc:identifier>
<dc:language>eng</dc:language>
<dc:relation>International Journal of Environmental Research and Public Health. 2022, V. 19, n. 15, 9533</dc:relation>
<dc:relation>https://doi.org/10.3390/ijerph19159533</dc:relation>
<dc:rights>Atribución 4.0 Internacional</dc:rights>
<dc:rights>http://creativecommons.org/licenses/by/4.0/</dc:rights>
<dc:rights>info:eu-repo/semantics/openAccess</dc:rights>
<dc:format>application/pdf</dc:format>
<dc:publisher>MDPI</dc:publisher>
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