2026-11-03T03:46:41Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/78132023-09-19T00:05:35Zcom_10259_6168com_10259_5086com_10259_2604com_10259_3593com_10259_5822col_10259_6169col_10259_3594col_10259_5823

Parra de la Parra, Sandra de la Tamayo Ramos, Juan Antonio Rubio Presa, Rubén Perez Antolin, Daniel Ruiz Fernández, Virginia Sanz Díez, Roberto Rumbo Lorenzo, Carlos Ventosa Arbaizar, Edgar 2023-09-18T10:08:42Z 2023-09-18T10:08:42Z 2023-09 1864-5631 http://hdl.handle.net/10259/7813 10.1002/cssc.202300626 1864-564X Viologen-derivatives are the most widely used redox organic molecules for neutral pH negative electrolyte of redox flow batteries. However, the long-established toxicity of the herbicide methyl-viologen raises concern for deployment of viologen-derivatives at large scale in flow batteries. Herein, we demonstrate the radically different cytotoxicity and toxicology of a series of viologen-derivatives in in vitro assays using model organisms representative of human and environmental exposure, namely human lung carcinoma epithelial cell line (A549) and the yeast Saccharomyces cerevisiae. The results show that safe viologen derivatives can be molecularly engineered, representing a promising family of negolyte materials for neutral redox flow batteries. The authors acknowledge financial support by the Spanish Government (Ministerio de Ciencia e Innovacion, Grants PID2021-124974OB-C22 and PID2020-115789GB-C21) and Ramon y Cajal award (RYC2018-026086-I) as well as the MeBattery project. MeBattery has received funding from the European Innovation Council of the European Union under Grant Agreement no. 101046742. This work was supported by the Regional Government of Castilla y Leon (Junta de Castilla y Leon) and by the Ministry of Science and Innovation MICIN and the European Union NextGenerationEU/PRTR. We also gratefully acknowledge Junta de Castilla y Leon (BU049P20) and FEDER for financial support. application/pdf eng Wiley-VCH ChemSusChem. 2023, e202300626 https://doi.org/10.1002/cssc.202300626 info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2021-124974OB-C22/ES/Procesos Redox mediados para baterias de flujo/ info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-115789GB-C21/ES/ESTRATEGIAS SINTETICAS SOSTENIBLES PARA LA TRANSFORMACION DIRECTA DE NITROCOMPUESTOS Y DESARROLLO DE NUEVAS REACCIONES CATALIZADAS POR ORO/ info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RYC2018-026086-I/ES/ info:eu-repo/grantAgreement/Junta de Castilla y León//BU049P20//Estrategias sintéticas sostenibles para la halogenación directa de nitrocompuestos y la preparación de electrolitos orgánicos para baterías de flujo redox/ info:eu-repo/grantAgreement/EC/HE/101046742/EU/MEDIATED BIPHASIC BATTERY/MeBattery Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess Cytotoxicity Toxicology Viologen derivatives Anolyte Redox flow battery Química analítica Química orgánica Chemistry, Analytic Chemistry, Organic On the Tunability of Toxicity for Viologen‐Derivatives as Anolyte for Neutral Aqueous Organic Redox Flow Batteries info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion ChemSusChem