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<mods:namePart>Cubo Delgado, Esther</mods:namePart>
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<mods:namePart>Trejo Gabriel y Galán, José Mª</mods:namePart>
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<mods:namePart>Macarrón Vicente, Jesus</mods:namePart>
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<mods:namePart>Cordero Guevara, José</mods:namePart>
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<mods:namePart>Louis, Elan D.</mods:namePart>
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<mods:namePart>Benito-León, Julián</mods:namePart>
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<mods:identifier type="issn">0887-8994</mods:identifier>
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<mods:identifier type="doi">10.1016/j.pediatrneurol.2011.03.003</mods:identifier>
<mods:abstract>Tic disorders constitute a neurodevelopmental disorder of childhood. This study sought to determine the prevalence of tic disorders in a school-based sample. A randomized sample of 1158 schoolchildren, based on clusters (classrooms) in the province of Burgos (Spain), was identified on a stratified sampling frame combining types of educational center and setting (mainstream schools and special education), using a two-phase approach (screening and diagnosis ascertainment by a neurologist). Tics with/without impairment criterion were diagnosed according to Diagnostic and Statistical Manual of Mental Disorders criteria. In mainstream schools, tics were observed in 125/741 students (16.86%; 95% confidence interval, 14.10-19.63), and were more frequent in boys (87/448, 19.42%; 95% confidence interval, 15.64-23.19) compared with girls (38/293, 12.96%; 95% confidence interval, 8.95-16.98; P = 0.03). In special education centers, tics disorders were observed in 11/54 of children (20.37%; 95% confidence interval, 8.70-32.03). Overall, tics with impairment criteria were less frequent than tics without impairment criteria (4.65% vs 11.85%, P &lt; 0.0001). The most frequent diagnoses involved chronic motor tics (6.07%) and Tourette syndrome (5.26%). Tic disorders are common in childhood, and the use or nonuse of impairment criteria exerts a significant impact on tic prevalence estimates.</mods:abstract>
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<mods:title>Prevalence of Tics in Schoolchildren in Central Spain: A Population-Based Study</mods:title>
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