2026-06-19T12:49:45Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/86472024-02-10T01:05:36Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594

Sarmiento, Jeymy T. Suarez Pantiga, Samuel Olmos, Andrea Varea, Teresa Asensio, Gregorio 2024-02-09T08:17:10Z 2024-02-09T08:17:10Z 2017-09 2155-5435 http://hdl.handle.net/10259/8647 10.1021/acscatal.7b02142 2155-5435 Immobilized sterically demanding NHC-Au(I) complexes silica-[(IPrR)Au]Cl and silica-[(IAdPrR)Au]Cl are synthesized and characterized. These complexes are suitable catalysts in typical homogeneous Au(I)-catalyzed alkyne reactions such as hydration, hydroamination, hydroarylation, or cycloisomerization. The results obtained with the immobilized catalysts in reactions in batch are comparable to those obtained with their homogeneous counterparts with the advantage of easily recovered and recycled in successive reactions. Their catalytic activity decreases when reused in batch reactions, probably because of crushing that is associated with magnetic stirring. In contrast, these immobilized catalysts are very effective when used under continuous flow conditions in which the same cartridge can be used to catalyze different types of reaction successively for a long period without any noticeable loss of activity. Support for this work was provided by the Ministerio de Economı́a y Competitividad (MINECO) and European Community Founds (FEDER) (No. CTQ2014-52769-C3-2-R). application/pdf eng ACS Publications ACS Catalysis. 2017, V. 7, n. 10, p. 7146-7155 https://doi.org/10.1021/acscatal.7b02142 Gold catalysis Immobilized catalyst Flow chemistry Alkyne NHC ligand Química orgánica Chemistry, Organic Silica-Immobilized NHC-Gold(I) Complexes: Versatile Catalysts for the Functionalization of Alkynes under Batch and Continuous Flow Conditions info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion info:eu-repo/semantics/openAccess ACS Catalysis 7 10 7146 7155