2026-09-19T17:36:38Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/88392024-03-19T01:05:16Zcom_10259_4219com_10259_5086com_10259_2604col_10259_4220

00925njm 22002777a 4500 dc Santos García, Diego author Deus-Fonticoba, Teresa de author Cores Bartolomé, Carlos author Suárez Castro, Ester author Hernández Vara, Jorge author Jesús, Silvia author Mir, Pablo author Cosgaya, Marina author José Martí, María author Pastor, Pau author Cabo López, Iria author Seijo, Manuel author Legarda, Inés author Vives Pastor, Bárbara author Caballol, Núria author Ruíz Martínez, Javier author Croitoru, Ioana author Cubo Delgado, Esther author Miranda, Javier author Alonso Losada, María Gema author Labandeira, Carmen author López Ariztegui, Nuria author Morales-Casado, Mabel author González Aramburu, Isabel author Infante, Jon author Escalante Arroyo, Sonia author Bernardo, Noemí author Blázquez Estrada, Marta author Menéndez González, Manuel author García Caldentey, Juan author Borrue, Carmen author Vela Desojo, Lydia author Catalán, María José author Gómez Mayordomo, Víctor author Kurtis, Mónica M. author Prieto, Cristina author Ordás Bandera, Carlos Manuel author Nogueira, Víctor author López Manzanares, Lydia author Ávila Rivera, María A. author Puente, Víctor author García Moreno, José Manuel author Solano Vila, Berta author Álvarez Saúco, María author Carrillo Padilla, Francisco author Martínez Castrillo, Juan Carlos author Sánchez Alonso, Pilar author Gastón, Itziar author Kulisevsky Bojarsky, Jaume author Valero, Caridad author Fabregues, Oriol de author González Ardura, Jessica author López Díaz, Luis M. author Martínez Martín, Pablo author COPPADIS Study Group author 2023-01 Background: There is a need for identifying risk factors for hospitalization in Parkinson’s disease (PD) and also interventions to reduce acute hospital admission. Objective: To analyze the frequency, causes, and predictors of acute hospitalization (AH) in PD patients from a Spanish cohort. Methods: PD patients recruited from 35 centers of Spain from the COPPADIS-2015 (COhort of Patients with PArkinson’s DIsease in Spain, 2015) cohort from January 2016 to November 2017, were included in the study. In order to identify predictors of AH, Kaplan-Meier estimates of factors considered as potential predictors were obtained and Cox regression performed on time to hospital encounter 1-year after the baseline visit. Results: Thirty-five out of 605 (5.8%) PD patients (62.5±8.9 years old; 59.8% males) presented an AH during the 1-year follow-up after the baseline visit. Traumatic falls represented the most frequent cause of admission, being 23.7% of all acute hospitalizations. To suffer from motor fluctuations (HR [hazard ratio] 2.461; 95% CI, 1.065–5.678; p = 0.035), a very severe non-motor symptoms burden (HR [hazard ratio] 2.828; 95% CI, 1.319–6.063; p = 0.008), falls (HR 3.966; 95% CI 1.757–8.470; p = 0.001), and dysphagia (HR 2.356; 95% CI 1.124–4.941; p = 0.023) was associated with AH after adjustment to age, gender, disease duration, levodopa equivalent daily dose, total number of non-antiparkinsonian drugs, and UPDRS-IIIOFF. Of the previous variables, only falls (HR 2.998; 95% CI 1.080–8.322; p = 0.035) was an independent predictor of AH. Conclusion: Falls is an independent predictor of AH in PD patients. 1877-7171 http://hdl.handle.net/10259/8839 10.3233/JPD-212539 1877-718X Falls Hospitalization Non-motor symptoms Parkinson’s disease Predictors Falls Predict Acute Hospitalization in Parkinson’s Disease