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<dc:creator>Santos García, Diego</dc:creator>
<dc:creator>Deus-Fonticoba, Teresa de</dc:creator>
<dc:creator>Cores Bartolomé, Carlos</dc:creator>
<dc:creator>Feal Painceiras, María</dc:creator>
<dc:creator>Íñiguez Alvarado, María Cristina</dc:creator>
<dc:creator>García Díaz, Iago</dc:creator>
<dc:creator>Jesús, Silvia</dc:creator>
<dc:creator>Buongiorno, María Teresa</dc:creator>
<dc:creator>Planellás, Lluis L.</dc:creator>
<dc:creator>Cosgaya, Marina</dc:creator>
<dc:creator>García Caldentey, Juan</dc:creator>
<dc:creator>Caballol, Núria</dc:creator>
<dc:creator>Legarda, Inés</dc:creator>
<dc:creator>Hernández Vara, Jorge</dc:creator>
<dc:creator>Cabo López, Iria</dc:creator>
<dc:creator>López Manzanares, Lydia</dc:creator>
<dc:creator>González Aramburu, Isabel</dc:creator>
<dc:creator>Ávila Rivera, María A.</dc:creator>
<dc:creator>Gómez Mayordomo, Víctor</dc:creator>
<dc:creator>Nogueira, Víctor</dc:creator>
<dc:creator>Puente, Víctor</dc:creator>
<dc:creator>Dotor, Julio</dc:creator>
<dc:creator>Borrue, Carmen</dc:creator>
<dc:creator>Solano Vila, Berta</dc:creator>
<dc:creator>Álvarez Saúco, María</dc:creator>
<dc:creator>Vela Desojo, Lydia</dc:creator>
<dc:creator>Escalante Arroyo, Sonia</dc:creator>
<dc:creator>Cubo Delgado, Esther</dc:creator>
<dc:creator>Carrillo Padilla, Francisco</dc:creator>
<dc:creator>Martínez Castrillo, Juan Carlos</dc:creator>
<dc:creator>Sánchez Alonso, Pilar</dc:creator>
<dc:creator>Alonso Losada, María Gema</dc:creator>
<dc:creator>López Ariztegui, Nuria</dc:creator>
<dc:creator>Gastón, Itziar</dc:creator>
<dc:creator>Kulisevsky Bojarsky, Jaume</dc:creator>
<dc:creator>Menéndez González, Manuel</dc:creator>
<dc:creator>Seijo, Manuel</dc:creator>
<dc:creator>Ruíz Martínez, Javier</dc:creator>
<dc:creator>Valero, Caridad</dc:creator>
<dc:creator>Kurtis, Mónica M.</dc:creator>
<dc:creator>González Ardura, Jessica</dc:creator>
<dc:creator>Alonso Redondo, Rubén</dc:creator>
<dc:creator>Ordás Bandera, Carlos Manuel</dc:creator>
<dc:creator>López Díaz, Luis M.</dc:creator>
<dc:creator>McAfee, Darrian</dc:creator>
<dc:creator>Martínez Martín, Pablo</dc:creator>
<dc:creator>Mir, Pablo</dc:creator>
<dc:creator>COPPADIS Study Group</dc:creator>
<dc:date>2023-03</dc:date>
<dc:description>Background: Although many studies have analyzed what factors contribute to caregiver burden in Parkinson’s disease (PD),&#xd;
there is currently no knowledge about how the status of the caregiver could impact the patient.&#xd;
Objective: The aim of this study was to analyze how the change in the caregiver’s status influences PD patients.&#xd;
Methods: PD patients and their caregivers who were recruited from January/2016 to November/2017 from 35 centers&#xd;
in Spain from the COPPADIS cohort were included in the study (V0). They were evaluated again at 2-year follow-up&#xd;
(V2). Caregivers completed the Zarit Caregiver Burden Inventory (ZCBI), Caregiver Strain Index (CSI), Beck Depression Inventory-II (BDI-II), and EUROHIS-QOL 8-item index (EUROHIS-QOL8) at V0 and V2. Multivariate models were&#xd;
used to analyze the impact of the change from V0 to V2 () on the caregiver’s status over the change in the patient’s&#xd;
status.&#xd;
Results: BDI-II and EUROHIS-QOL8 in the caregiver predicted BDI-II ( = 0.32; p &lt; 0.0001; R2 = 0.71) and&#xd;
EUROHIS-QOL8 ( = 0.39; p &lt; 0.0001; R2 = 0.68) in the patient, respectively. Variables related to the caregiver were&#xd;
not associated with changes in the patient´s health-related QoL (PDQ-39 [39-item Parkinson’s disease Questionnaire]) or&#xd;
autonomy for activities of daily-living (ADLS [Schwab &amp; England Activities of Daily Living Scale]).&#xd;
Conclusion: The change in the caregiver’s mood and global QoL was associated with the change in the patient’s mood and&#xd;
global QoL, respectively, independently of other variables of the disease influencing both patient´s aspects. Based on this&#xd;
finding, it could be of great importance to detect depression in the principal caregiver of a patient and act on it as earlier as&#xd;
possible.</dc:description>
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<dc:identifier>http://hdl.handle.net/10259/8856</dc:identifier>
<dc:language>eng</dc:language>
<dc:publisher>IOS Press</dc:publisher>
<dc:title>Changes in Principal Caregiver Mood Affects the Mood of the Parkinson’s Disease Patient: The Vicious Cycle of Illness</dc:title>
<dc:type>info:eu-repo/semantics/article</dc:type>
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