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oai:riubu.ubu.es:10259/88562024-03-21T01:05:05Zcom_10259_4219com_10259_5086com_10259_2604col_10259_4220

00925njm 22002777a 4500 dc Santos García, Diego author Deus-Fonticoba, Teresa de author Cores Bartolomé, Carlos author Feal Painceiras, María author Íñiguez Alvarado, María Cristina author García Díaz, Iago author Jesús, Silvia author Buongiorno, María Teresa author Planellás, Lluis L. author Cosgaya, Marina author García Caldentey, Juan author Caballol, Núria author Legarda, Inés author Hernández Vara, Jorge author Cabo López, Iria author López Manzanares, Lydia author González Aramburu, Isabel author Ávila Rivera, María A. author Gómez Mayordomo, Víctor author Nogueira, Víctor author Puente, Víctor author Dotor, Julio author Borrue, Carmen author Solano Vila, Berta author Álvarez Saúco, María author Vela Desojo, Lydia author Escalante Arroyo, Sonia author Cubo Delgado, Esther author Carrillo Padilla, Francisco author Martínez Castrillo, Juan Carlos author Sánchez Alonso, Pilar author Alonso Losada, María Gema author López Ariztegui, Nuria author Gastón, Itziar author Kulisevsky Bojarsky, Jaume author Menéndez González, Manuel author Seijo, Manuel author Ruíz Martínez, Javier author Valero, Caridad author Kurtis, Mónica M. author González Ardura, Jessica author Alonso Redondo, Rubén author Ordás Bandera, Carlos Manuel author López Díaz, Luis M. author McAfee, Darrian author Martínez Martín, Pablo author Mir, Pablo author COPPADIS Study Group author 2023-03 Background: Although many studies have analyzed what factors contribute to caregiver burden in Parkinson’s disease (PD), there is currently no knowledge about how the status of the caregiver could impact the patient. Objective: The aim of this study was to analyze how the change in the caregiver’s status influences PD patients. Methods: PD patients and their caregivers who were recruited from January/2016 to November/2017 from 35 centers in Spain from the COPPADIS cohort were included in the study (V0). They were evaluated again at 2-year follow-up (V2). Caregivers completed the Zarit Caregiver Burden Inventory (ZCBI), Caregiver Strain Index (CSI), Beck Depression Inventory-II (BDI-II), and EUROHIS-QOL 8-item index (EUROHIS-QOL8) at V0 and V2. Multivariate models were used to analyze the impact of the change from V0 to V2 () on the caregiver’s status over the change in the patient’s status. Results: BDI-II and EUROHIS-QOL8 in the caregiver predicted BDI-II ( = 0.32; p < 0.0001; R2 = 0.71) and EUROHIS-QOL8 ( = 0.39; p < 0.0001; R2 = 0.68) in the patient, respectively. Variables related to the caregiver were not associated with changes in the patient´s health-related QoL (PDQ-39 [39-item Parkinson’s disease Questionnaire]) or autonomy for activities of daily-living (ADLS [Schwab & England Activities of Daily Living Scale]). Conclusion: The change in the caregiver’s mood and global QoL was associated with the change in the patient’s mood and global QoL, respectively, independently of other variables of the disease influencing both patient´s aspects. Based on this finding, it could be of great importance to detect depression in the principal caregiver of a patient and act on it as earlier as possible. 1877-7171 http://hdl.handle.net/10259/8856 10.3233/JPD-225014 1877-718X Caregiver Longitudinal Mood Parkinson’s disease Quality of life Changes in Principal Caregiver Mood Affects the Mood of the Parkinson’s Disease Patient: The Vicious Cycle of Illness