Synthesis of 1,4-ketoaldehydes and 1,4-diketones by Mo-catalyzed oxidative cleavage of cyclobutane-1,2-diols

2026-06-19T12:54:06Zhttps://riubu.ubu.es/oai/request

oai:riubu.ubu.es:10259/93242024-07-02T00:05:29Zcom_10259_3596com_10259_5086com_10259_2604com_10259_3593col_10259_3597col_10259_3594

Synthesis of 1,4-ketoaldehydes and 1,4-diketones by Mo-catalyzed oxidative cleavage of cyclobutane-1,2-diols Gómez Gil, Sara Rubio Presa, Rubén Hernández Ruiz, Raquel Suarez Pantiga, Samuel Pedrosa Sáez, María de los Remedios Sanz Díez, Roberto A new two-step procedure for the synthesis of 1,4-dicarbonyls has been developed involving an efficient and clean Mo-catalyzed oxidative cleavage of cyclobutane-1,2-diols with DMSO, which is used as solvent and oxidant. The required starting glycols were prepared by nucleophilic additions of organolithiums and Grignard reagents to easily available 2-hydroxycyclobutanones. 2024-07-01 2024-07-01 2023-04-26 info:eu-repo/semantics/article 1477-0520 http://hdl.handle.net/10259/9324 10.1039/D3OB00436H 1477-0539 eng Organic & Biomolecular Chemistry. 2023, V. 21, n. 20, p. 4185-4190 https://doi.org/10.1039/D3OB00436H http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess Atribución-NoComercial 4.0 Internacional Royal Society of Chemistry