2026-07-30T19:15:46Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/93362024-07-03T00:05:19Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594
Synthesis of 4‐Furan‐ and 4‐Pyrrol‐3‐yl‐2H‐chromenes from Naturally‐occurring Compounds by Gold(I)‐Catalyed Domino Reactions
Solas Luera, Marta
Renedo Peña, Lorena
Suárez Pantiga, Samuel
Sanz Díez, Roberto
Annulation
Chromenes
Furans
Gold
Hydroarylation
Pyrroles
A gold-catalyzed cascade double cyclization reaction has been designed to synthesize heterobiaryl compounds such as furanyl and pyrrolyl 2H-chromenes from bis(alkynyl)-1,2-diols and 1,2-amino alcohols. The starting materials are readily available from biomass platform molecules such as α-hydroxy acids and α-amino acids. The process involves an initial heterocyclodehydration step enabling the formation of the furan or pyrrole ring, followed by an alkyne hydroarylation to form the chromene core.
2024-07-02
2024-07-02
2023-05-24
info:eu-repo/semantics/article
1615-4150
http://hdl.handle.net/10259/9336
10.1002/adsc.202300300
1615-4169
eng
Advanced Synthesis & Catalysis. 2023, V. 365, n. 12, p. 2049-2056
https://doi.org/10.1002/adsc.202300300
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
Atribución-NoComercial 4.0 Internacional
Wiley