2024-03-28T22:40:47Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/53452022-04-08T10:18:38Zcom_10259_4376com_10259_5086com_10259_2604col_10259_4377
Molinero Abad, Begoña
Pérez Ruiz, Lydia
Izquierdo Bote, Daniel
Escudero Barbero, Isabel
Arcos Martínez, Julia
2020-06-17T13:27:02Z
2020-06-17T13:27:02Z
2019-01
0039-9140
http://hdl.handle.net/10259/5345
10.1016/j.talanta.2018.09.072
The monitoring of marine dinophysistoxin okadaic acid in seawater can serve as an early alert system for preventing the potential negative effects this toxin can have on the food industry and human health in general. A disposable sensor system for electrochemical detection of this toxin has been developed using screen-printed electrodes. The method described is based on the inhibition of protein phosphatase type 2A by okadaic acid, evaluating the enzyme activity. p-Nitrophenyl phosphate, 4-methylumbelliferyl phosphate and phenyl phosphate have been tested as substrates achieving good limits of detection of 2.7·10–12 M of okadaic acid. The proposed method has been successfully applied to okadaic acid determination in seawater samples. A study of divalent cations present in seawater that can interfere with the measurement has been carried out. The electrode systems were printed on both rigid and textile backing materials to observe the influence of those materials on the final performance of the sensor.
Ministerio de Ciencia e Innovación (MICINN) (TEC2013-405661-P) Ministerio de Economía y Competitividad (MINECO) and European Regional Development Fund (FEDER) (MUSSEL RTC-2015-4077-2).
application/pdf
eng
Elsevier
Talanta. 2019, V. 192, p. 347-352
https://doi.org/10.1016/j.talanta.2018.09.072
info:eu-repo/grantAgreement/MICINN/TEC2013-405661-P
info:eu-repo/grantAgreement/MINECO/MUSSEL RTC-2015-4077-2)
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
Okadaic acid
Screen printed electrodes
Textile sensors
Seawater
PP2A
Química analítica
Chemistry, Analytic
Sensor system based on flexible screen-printed electrodes for electrochemical detection of okadaic acid in seawater
info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
Talanta
192
347
352