2024-03-28T17:09:48Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/42812022-04-29T12:02:48Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594
Feberero, Claudia
Velasco, Rocío
Sanz Díez, Roberto
2016-11
New dihalosalicylamides and trihalophenol derivatives have been synthesized from easily available O-(3,n-dihalophenyl) N,N-diethylcarbamates by using a directed ortho-metalation (DoM) strategy. The o-lithiation reactions with sBuLi take place regioselectively at the doubly activated C-2 position, which demonstrates the ability of O-carbamates as directed metalating groups. In addition, highly functionalized arylnitriles were accessed from organolithium intermediates by using a tandem transnitrilation/SNAr reaction sequence.
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http://hdl.handle.net/10259/4281
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Wiley-VCH Verlag
ortho-Lithiation Reactions of O-(3,n-Dihalophenyl) N,N-Diethylcarbamates: Synthesis of Dihalosalicylamides and 2,3,n-Trihalophenol Derivatives
info:eu-repo/semantics/article
TEXT
RIUBU. Repositorio Institucional de la Universidad de Burgos
Hispana