2024-03-29T05:57:17Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/43922022-05-20T13:22:32Zcom_10259_4862com_10259_5086com_10259_2604col_10259_4863
Phenotypic, molecular characterization, antimicrobial susceptibility and draft genome sequence of Corynebacterium argentoratense strains isolated from clinical samples
Fernández Natal, Isabel
Sáez Nieto, J. A.
Rodríguez Lázaro, David
Valdezate Ramos, S.
Parras Padilla, T.
Medina, M. J.
Rodríguez Pollán, R. H.
Blom, J.
Tauch, A.
Soriano, F.
Antimicrobial resistance
clinical infections
Corynebacterium argentoratense
MALDI-TOF
whole genome sequencing
Microbiology
Microbiología
During a 12-year period we isolated five Corynebacterium argentoratense strains identified by phenotypic methods, including the use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) and 16S rRNA gene sequencing. In addition, antimicrobial susceptibility was determined, and genome sequencing for the detection of antibiotic resistance genes was performed. The organisms were isolated from blood and throat cultures and could be identified by all methods used. All strains were resistant to cotrimoxazole, and resistance to β-lactams was partly present. Two strains were resistant to erythromycin and clindamycin. The draft genome sequences of theses isolates revealed the presence of the erm(X) resistance gene that is embedded in the genetic structure of the transposable element Tn5423. Although rarely reported as a human pathogen, C. argentoratense can be involved in bacteraemia and probably in other infections. Our results also show that horizontal transfer of genes responsible for antibiotic resistance is occurring in this species.
Supported in part by the Gerencia Regional de
Salud, Junta de Castilla y León, Spain (research project GRS
698/A/2011)
2017-03-29T09:34:05Z
2017-03-29T09:34:05Z
2016-03
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://hdl.handle.net/10259/4392
eng
New Microbes and New Infections. 2016, V. 10, p. 116–121
http://dx.doi.org/10.1016/j.nmni.2016.01.007
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
application/pdf
Elsevier
https://riubu.ubu.es/bitstream/10259/4392/7/Fern%c3%a1ndez-NMNI_2016.pdf.jpg
Hispana
TEXT
http://creativecommons.org/licenses/by-nc-nd/4.0/
RIUBU. Repositorio Institucional de la Universidad de Burgos
http://hdl.handle.net/10259/4392