2024-03-29T01:52:15Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/42422021-11-10T09:38:24Zcom_10259_3593com_10259_5086com_10259_2604col_10259_3594
00925njm 22002777a 4500
dc
Guilarte Moreno, Verónica
author
Castroviejo Fernández, Mª Pilar
author
Álvarez Manuel, Estela
author
Sanz Díez, Roberto
author
2011-09
A new route to regioselectively dialkoxy-functionalized benzo[b]furan derivatives has been developed from 3-halo-2-iodoanisoles
bearing an additional methoxy group, which have been accessed through an ortho-zincation/iodination reaction. Two palladiumcatalyzed
processes, namely a Sonogashira coupling followed by a tandem hydroxylation/cyclization sequence, give rise to new and
interesting dimethoxy-substituted benzo[b]furans.
1860-5397
http://hdl.handle.net/10259/4242
10.3762/bjoc.7.146
benzo[b]furans
o-zincation
palladium
selectivity
Combined directed ortho-zincation and palladiumcatalyzed strategies: Synthesis of 4,n-dimethoxysubstituted benzo[b]furans