2024-03-28T17:34:46Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/43612022-12-19T13:18:42Zcom_10259_4354com_10259_5086com_10259_2604com_10259_4363com_10259_4365col_10259_4355col_10259_4364col_10259_4366
00925njm 22002777a 4500
dc
Díaz de Greñu Puertas, Borja
author
García Calvo, José
author
Cuevas Vicario, José Vicente
author
García Herbosa, Gabriel
author
García Ruiz, Begoña
author
Busto Vázquez, Natalia
author
Ibeas Cortes, Saturnino
author
Torroba Pérez, Tomás
author
Torroba, Blanca
author
Herrera, Antonio
author
Pons, Sebastian
author
2015-07
Selected new fluorogenic probes that interact in different ways with Hg2+ and MeHg+ have been prepared
and used for the chemical speciation of both cations in aqueous solution as well as in HEK293 cells. The best
selective speciation of Hg2+ and MeHg+ has been achieved by in vitro approaches based on fluorogenic
probes supported in cultured cells, due to the particular sensitivity of the HEK293 cells to permeation by
Hg2+, MeHg+ and the fluorogenic probes. In particular, MeHg+ was selectively detected in cell nuclei by
probe JG45.
http://hdl.handle.net/10259/4361
Chemical speciation of MeHg+ and Hg2+ in aqueous solution and HEK cells nuclei by means of DNA interacting fluorogenic probes