2024-03-28T20:42:46Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/55762023-02-27T23:42:06Zcom_10259_4244com_10259_5086com_10259_2604col_10259_4245
00925njm 22002777a 4500
dc
Melgosa Gómez, Rodrigo
author
Sanz Díez, Mª Teresa
author
Beltrán Calvo, Sagrario
author
2021-02
Driven by growing prevalence of chronic diseases and consumer’s health awareness, food supplements and nutraceuticals based on omega-3 polyunsaturated fatty acids (PUFAs) are extensively marketed nowadays. However, commercial omega-3 concentrates still present quality issues related to their purity, bioavailability, and easily-oxidizable nature, compelling the industry to seek for more efficient extraction, concentration and formulation methods. Technologies based on the use of supercritical CO2 (scCO2) are a promising alternative, replacing conventional organic solvents and providing milder conditions and an inert atmosphere, which reduce the risk of oxidation. The present review analyzes the latest advances on the use of scCO2 for processing omega-3 PUFAs, focusing on its application in biorefinery strategies for the valorization of fish by-products. Still, further research on process fundamentals is necessary in order to increase the omega-3 yield and purity while reducing the use of energy and auxiliary materials, especially in the transesterification and concentration steps.
0896-8446
http://hdl.handle.net/10259/5576
10.1016/j.supflu.2020.105121
Fish oil
Omega-3 polyunsaturated fatty acids
Biorefinery
Supercritical carbon dioxide
Enzyme
Supercritical CO2 processing of omega-3 polyunsaturated fatty acids – Towards a biorefinery for fish waste valorization